Predictive Biomarkers in Cancer

Dear Colleagues,

In recent years, functional gene analysis of malignant tumors has progressed, and many cancer-related genes have been identified. Detection of genetic mutations by immunohistochemical staining and PCR methods using cancer tissues, as well as detection of somatic mutations useful as biomarkers of malignancy from genetic analysis using next-generation sequencers (NGS), is now providing important information for determining cancer treatment strategies.

Histopathological diagnosis is an important tool in the conventional diagnosis of cancer. However, in the treatment of cancer, many therapeutic agents based on genetic abnormalities of cancer-related molecules have been challenged as molecularly targeted therapies, resulting in an improved prognosis.

We hope that this Special Issue will lead to the discovery of new predictive biomarkers in cancer, including histological information obtained from histopathological diagnosis, and to the improvement of prognosis, thereby expanding the range of knowledge from basic research to clinical application.

Dr. Tomomi Fujii
Guest Editor

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• next-generation sequencers (NGS)
• cancer
• molecular biology
• pathology
• cytology
• genomic diagnosis
• molecular pathology
• molecular target
• urogenital tumor
• lung cancer
• microRNA