Evidence-Based Pharmaceutical Care and Rational Antibiotic Use

Dear Colleagues,

At present, the global crisis of bacterial resistance triggered by antibiotic abuse is becoming increasingly severe and has become a major challenge threatening public health security. In clinical practice, the use of some antibiotics lacks an evidence-based basis, with inappropriate dosages and unreasonable treatment courses, which not only reduces therapeutic effects and increases the risk of adverse reactions, but also accelerates the emergence and spread of resistant strains. Against this background, the launch of the Special Issue, “Evidence-Based Pharmaceutical Care and Rational Antibiotic Use”, aims to integrate cutting-edge research results at home and abroad, build an academic exchange platform, promote the deep integration of evidence-based concepts and clinical application of antibiotics, and provide scientific guidance for standardized medication use.

This Special Issue focuses on collecting high-quality research results in three major directions: First, research on the rational use of antibiotics based on evidence-based pharmacy, including the analysis of evidence-based evidence for optimal antibiotic regimens for different infection types, individualized dose optimization, treatment course adjustment, as well as the formulation and implementation effect evaluation of clinical pathways; Second, research on the application of precision medication technology in antimicrobial therapy, covering antibiotic selection guided by genetic testing, the role of therapeutic drug monitoring (TDM) in improving medication safety and efficacy, and the development of artificial intelligence-assisted antimicrobial treatment decision systems; Third, research on antibiotic pharmacovigilance, focusing on active monitoring and risk assessment of antibiotic adverse reactions, safe management of antibiotic use in special populations (such as the elderly, children, and pregnant women), and pharmaceutical intervention strategies related to the prevention and control of resistant bacterial infections.

By gathering multi-field research results, this Special Issue will provide practical academic references for clinical pharmacists, physicians, and researchers, help promote the improvement of rational antibiotic use levels, curb the spread of bacterial resistance, and ensure public medication safety and health.

Acknowledgments: Mr. Pengxiang Zhou will be participating in this Special Issue as a specialist advisor. We would like to thank him for his contributions to this Special Issue.

Prof. Dr. Suodi Zhai
Prof. Dr. Siyan Zhan
Guest Editors

Manuscript Submission Information

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• rational antibiotic use
• bacterial resistance
• medical institutions
• optimization of antibiotic usage and dosages
• prescription