Infection, Immune Escape, and Pathogenic Mechanism of African Swine Fever Virus
A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 2318
Special Issue Editor
Interests: virus; pathogenicity; innate immune; signaling pathway; host–virus interaction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
African swine fever (ASF) is a notifiable animal disease of the World Organization for Animal Health. African swine fever virus (ASFV)-infected pigs have a high mortality approaching 100%, and ASF has dealt a heavy blow to the global pig industry since it was introduced into China in 2018. ASF has spread rapidly worldwide due to the lack of safe, effective, and quality-controlled vaccines. However, the pathogenesis, immune evasion, and immune protection mechanism of ASFV is not fully understood, which brings great difficulties to the research and development of a safe and efficient ASF vaccine. Therefore, it is urgent to study the infection and pathogenesis of ASFV as well as the molecular and cellular mechanisms of how ASFV escapes the host innate and adaptive immune responses. The aim of this Special Issue is to study the infection and pathogenesis of ASFV as well as the molecular and cellular mechanisms of how ASFV escapes the host innate and adaptive immune responses.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: 1) the function of ASFV genes, 2) mechanism of ASFV infection and pathogenicity, 3) mechanisms of ASFV negatively regulating innate immune, 4) mechanism of ASFV regulating inflammatory response, 5) mechanisms of ASFV regulating autophagy, 6) mechanisms of ASFV inducing cell death, and 7) molecular and cellular mechanism of immune protection against ASFV.
We look forward to receiving your contributions.
Dr. Li Huang
Guest Editor
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Keywords
- ASF
- ASFV
- pathogenesis
- immune evasion
- immune protection
- host–virus interaction
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