Special Issue "Inside the Genetics and Genomics of Variability and Functionality in Vertebrates: Current Applications and Perspectives"

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Genetics and Genomics".

Deadline for manuscript submissions: 28 February 2021.

Special Issue Editors

Dr. Vincenzo Landi
Website SciProfiles
Guest Editor
Animal Breeding and Genetics, Department of Veterinary Medicine, University of Bari "Aldo Moro", SP. 62 per Casamassima km. 3, 70010 Valenzano (BA), Italy
Interests: Genomics; Animal Genetics; Animal Breeding
Dr. Elena Ciani
Website
Guest Editor
Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari "Aldo Moro", Via Amendola 165/a, 70126 Bari, Italy
Interests: Genomics; Animal Genetics; Animal Breeding; biostatistics

Special Issue Information

Dear Colleagues,

In the last years, applications of genetics and genomics have entered the study of vertebrates due not only to the availability of platforms that allow rapid and affordable study of the DNA sequence and its variation, with the possibility of generating amount of information that was unthinkable up to a few years ago, but also to the exponential growth of statistical and information technology (IT) applications that allow managing and maximizing the available information. The challenge in the post-genomic era is extracting functional or evolutionary inferences from DNA data. Simultaneously, tools such as microsatellites, although scaled down in use, continue to be used for the study of the structure and variability of animal populations, especially when updated technical and adequate economic means are not available.

In this Special Issue, we propose a collection of works on the possible applications of genetics and genomics to the various fields of the study of vertebrate populations (both domestic and wild), with particular attention to those applications aimed at current issues of climate change, conservation, and sustainable management and improvement of genetic resources.

Dr. Vincenzo Landi
Dr. Elena Ciani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Single nucleotide polymorphisms (SNPs)
  • Microsatellites (short tandem repeats, STRs)
  • Copy number variations (CNVs)
  • Selection signatures
  • Functional genomics
  • Gene flow Admixture
  • Phylogeography

Published Papers (1 paper)

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Research

Open AccessArticle
Genomic Tools for the Conservation and Genetic Improvement of a Highly Fragmented Breed—The Ramo Grande Cattle from the Azores
Animals 2020, 10(6), 1089; https://doi.org/10.3390/ani10061089 - 24 Jun 2020
Abstract
Ramo Grande is a local cattle breed raised in the archipelago of Azores, with a small and dispersed census, where inbreeding control is of utmost importance. A single nucleotide polymorphism (SNP) Beadchip array was used to assess inbreeding, by analysis of genomic regions [...] Read more.
Ramo Grande is a local cattle breed raised in the archipelago of Azores, with a small and dispersed census, where inbreeding control is of utmost importance. A single nucleotide polymorphism (SNP) Beadchip array was used to assess inbreeding, by analysis of genomic regions harboring contiguous homozygous genotypes named runs of homozygosity (ROH), and to estimate past effective population size by analysis of linkage disequilibrium (LD). Genetic markers associated with production traits were also investigated, exploiting the unique genetic and adaptation features of this breed. A total of 639 ROH with length >4 Mb were identified, with mean length of 14.96 Mb. The mean genomic inbreeding was 0.09, and long segments of ROH were common, indicating recent inbred matings. The LD pattern indicates a large effective population size, suggesting the inflow of exotic germplasm in the past. The genome-wide association study identified novel markers significantly affecting longevity, age at first calving and direct genetic effects on calf weight. These results provide the first evidence of the association of longevity with genes related with DNA recognition and repair, and the association of age at first calving with aquaporin proteins, which are known to have a crucial role in reproduction. Full article
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