Immune-Related Genes in Aquatic Animals
A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Genetics and Genomics".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 2531
Special Issue Editors
Interests: aquatic animal; molecular immunology; DNA methylation; environmental immunology; physiology
Interests: aquatic animal; viral diseases prevention; molecular immunology; physiology; germ cells development; sex-controlled breeding
Interests: crab and shrimp; molecular immunity; multi-omics; non-coding RNA; pathogenic molecular mechanism of aquatic pathogens; molecular mechanism of aquatic disease resistance; crustacean molecular genetics and breeding
Special Issue Information
Dear Colleagues,
As an important branch of immunology, molecular immunology has developed rapidly in recent years. Although it is a young discipline, it plays an important role in immunology. The development of fish’s and shellfish’s molecular immunology has prompted more and more aquatic immune-related genes and regulatory factors to be cloned and studied. In view of the related role of these genes and their regulatory factors in the immune response, scholars around the world are gradually taking the expression of genes as an evaluation index of fish and shellfish health. At the same time, these studies also provide a basis for exploring the molecular mechanisms of fish and shellfish immunity.
In recent years, with the rapid development of high-density industrialized breeding and the increasingly serious pollution of the breeding environment, various diseases that endanger the health of fish and shellfish have appeared one after another, which have brought serious economic losses to fish and shellfish farming. Thereinto, as a low vertebrate, fish have a relatively low specific immune response ability, and nonspecific immune defense plays an important role in resisting the invasion of external pathogens. Similarly, shellfish, as invertebrates, only have a nonspecific immune response ability. There are many kinds of immune-related genes and their regulatory factors involved in the process of fish and shellfish immune defense, but relatively few genes and their regulatory factors have been studied in terms of molecular immunity.
This research topic focuses primarily on the profiling and functional characterization of immune-related genes and their regulatory factors in aquatic animals, including the influence of the immune mode on fish and shellfish immune responses at the gene level and epigenetics: DNA methylation, histone methylation and acetylation, chromatin accessibility, and noncoding RNA. They are abundantly expressed in the genome and play an important role in regulating gene expression. Through the above research, not only can epigenetic molecular markers be found in aquatic organisms, but a link between genetic information and growth, reproduction, and diseases can also be established to improve the breeding of aquatic organisms.
Dr. Feng He
Dr. Lang Gui
Dr. Jiangtao Ou
Guest Editors
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Keywords
- aquatic animal
- aquatic pathogen
- interaction between pathogen and host
- innate and adaptive immunity
- molecular immunology
- nutritional immunology
- environmental immunology
- multiple omics research
- disease prevention and control
- breeding for disease resistance
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