Algorithms for Biological Network Modelling

Dear Colleagues,

Computational models of biological networks have come to occupy a central role in quantitative biology and medicine, enabling precise predictions to be made and tested regarding the effects of chemical and genetic perturbations. However, a key bottleneck in constructing predictive models is the process of calibrating parameters to experimental data, particularly in view of the exponential increase in model parameters with system size.

This Special Issue will bring together cutting-edge methods from diverse computational disciplines that are currently being employed to address this important problem. Of particular interest are (i) methods from evolutionary computing to efficiently explore and characterize the design space (e.g., evolutionary algorithms, multi-objective optimisation, surrogate-assisted optimisation, landscape-aware heuristic search) and (ii) methods from applied mathematics to construct model formulations that reduce complexity whilst preserving predictive capacity (e.g., logic-based models).

We encourage submissions across a broad range of application domains, including—but not restricted to—gene regulatory network modelling, metabolic modelling, synthetic biology and computational neuroscience.

Dr. Ozgur Akman
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Algorithms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.