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Lymphatics, Volume 3, Issue 4

December 2025 - 21 articles

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Articles (21)

  • Article
  • Open Access
38 Views
13 Pages

Histamine Deficiency Inhibits Lymphocyte Infiltration in the Lacrimal Gland of Aged Mice

  • Hirotada Otsuka,
  • Yusuke Tsunoyama,
  • Miki Koh,
  • Satoshi Soeta and
  • Naoko Nonaka

17 December 2025

Aging is associated with chronic low-grade inflammation of exocrine glands, such as the lacrimal glands. Histamine, synthesized by histidine decarboxylase (HDC), is implicated in immune modulation; however, its role in age-related lacrimal gland infl...

  • Commentary
  • Open Access
59 Views
8 Pages

17 December 2025

Chronic lymphocytic leukemia (CLL) is an indolent malignancy with modest proliferation in the lymph nodes and accumulation of quiescent B cells in the peripheral blood. Targeted agents, including BTK inhibitors such as ibrutinib and the BCL2 antagoni...

  • Review
  • Open Access
154 Views
10 Pages

12 December 2025

Lymphatic malformations are rare congenital anomalies that range from small, self-limited lesions to large, rapidly expanding masses capable of causing serious perinatal complications, including hydrops fetalis, polyhydramnios, airway obstruction, an...

  • Article
  • Open Access
168 Views
17 Pages

The ADRENALINE pilot study explores the role of physical activity in health outcomes among patients with Chronic Lymphocytic Leukemia (CLL), focusing on disease markers, functional capacity, immune parameters, and quality of life. This baseline analy...

  • Correction
  • Open Access
71 Views
1 Page

Correction: Ramos Peñafiel et al. Effect of ABCB1 Expression on Measurable Residual Disease in Adult Patients with Acute Lymphoblastic Leukemia. Lymphatics 2025, 3, 6

  • Christian Omar Ramos Peñafiel,
  • Adolfo Martínez Tovar,
  • Daniela Pérez Sámano,
  • Rafael Cerón Maldonado,
  • Adán Germán Gallardo Rodríguez,
  • Carlos Martínez Murillo and
  • Irma Olarte Carrillo

In the original publication [...]

  • Review
  • Open Access
353 Views
11 Pages

Lymphatic Spread of Non-Small-Cell Lung Cancer: Mechanisms, Patterns, Staging, and Diagnosis

  • Mohamed Salih Makawi,
  • Stephen Ciaccio,
  • Asad Khan,
  • Alireza Nathani and
  • Ronaldo Ortiz-Pacheco

Lung cancer is the leading cause of cancer-related death worldwide. Lymph node involvement affects staging and, therefore, prognosis. Understanding lymph node drainage, metastatic patterns, and different sampling techniques contributes to the overall...

  • Case Report
  • Open Access
347 Views
14 Pages

Indocyanine Green-Guided Lymphatic Sparing Surgery for Lipedema: A Case Series

  • Michael Mazarei,
  • Shayan Mohammad Sarrami,
  • Darya Fadavi,
  • Meeti Mehta,
  • Anna Bazell and
  • Carolyn De La Cruz

Background: Lipedema is a progressive adipofascial disorder marked by painful nodular fat deposition that is often mistaken for obesity. While tumescent liposuction reduces limb volume with relative lymphatic safety, persistent large, painful lobules...

  • Review
  • Open Access
219 Views
18 Pages

29 November 2025

Indolent lymphoproliferative diseases or disorders (LPDs) derived from T cells or Natural Killer (NK) cells may be neoplastic or non-neoplastic, which are often difficult to distinguish from each other and from their aggressive counterparts. The etio...

  • Case Report
  • Open Access
157 Views
7 Pages

Reactive Intravascular B-Cell Immunoblastic Proliferation: A Recently Described Entity and a Mimicker of Intravascular Lymphoma

  • Nicolas Ulrich Edgar,
  • Seodam Kwak,
  • Kelsey Baron,
  • Archana Agarwal,
  • Anton Rets and
  • Anna Shestakova

26 November 2025

Reactive intralymphovascular immunoblastic proliferation (ILVIP) is a rare and diagnostically challenging entity that can closely mimic intravascular large B-cell lymphoma (IVLBCL). We report the comprehensive clinicopathologic features of two patien...

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Lymphatics - ISSN 2813-3307