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Biophysica, Volume 5, Issue 4

December 2025 - 21 articles

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Articles (21)

  • Article
  • Open Access
84 Views
17 Pages

15 December 2025

We investigated the roles and regulation of contractile and sodium ion transporter proteins in the pathogenesis of diarrhea in the acute ulcerative colitis. Acute ulcerative colitis was induced in male Sprague-Dawley rats using dextran sulfate sodium...

  • Review
  • Open Access
117 Views
25 Pages

Integrating AI with Cellular and Mechanobiology: Trends and Perspectives

  • Sakib Mohammad,
  • Md Sakhawat Hossain and
  • Sydney L. Sarver

14 December 2025

Mechanobiology explores how physical forces and cellular mechanics influence biological processes. This field has experienced rapid growth, driven by advances in high-resolution imaging, micromechanical testing, and computational modeling. At the sam...

  • Article
  • Open Access
245 Views
14 Pages

Forces exerted by cells due to their internal contractility play fundamental roles in a host of processes, including adhesion, migration, survival and differentiation. Traction force microscopy (TFM) enables the determination of forces exerted by cel...

  • Article
  • Open Access
197 Views
22 Pages

Estimation and Classification of Coffee Plant Water Potential Using Spectral Reflectance and Machine Learning Techniques

  • Deyvis Cabrini Teixeira Delfino,
  • Danton Diego Ferreira,
  • Margarete Marin Lordelo Volpato,
  • Vânia Aparecida Silva,
  • Renan Teixeira Delfino,
  • Christiano Sousa Machado de Matos and
  • Meline de Oliveira Santos

Water potential is an important indicator used to study water relations in plants, as it reflects the level of hydration in their tissues. There are different numerical variables that describe plant properties and can be acquired from leaf reflectanc...

  • Article
  • Open Access
325 Views
11 Pages

A rapid, colorimetric sensor for histamine detection is presented using citrate-stabilized gold nanoparticles enhanced with Cu2+ coordination. The sensing mechanism involves dual recognition: protonated histamine first adsorbs electrostatically onto...

  • Communication
  • Open Access
169 Views
7 Pages

Membrane Depth Measurements of E Protein by 2H ESEEM Spectroscopy in Lipid Bilayers

  • Andrew K. Morris,
  • Robert M. McCarrick and
  • Gary A. Lorigan

26 November 2025

A topological analysis was performed by taking ESEEM measurements of site-specifically labeled E protein from SARS-CoV-2. The intensity of deuterium modulation arising from either deuterated solvent or deuterated lipid acyl chains revealed exposure t...

  • Review
  • Open Access
446 Views
25 Pages

21 November 2025

Protein droplets exhibit complex self-assembly and deposition behaviors driven by evaporation, which has attracted increasing attention in recent years. Under evaporation, limited volume and locally concentrated protein solutions can undergo liquid&n...

  • Article
  • Open Access
367 Views
26 Pages

18 November 2025

We present a proof-of-concept study using a laser trapping (LT) approach to characterize hemoglobin variants through controlled dielectric breakdown of red blood cell membranes. Using a 1064 nm infrared laser, we analyzed 62 cells from each of four h...

  • Article
  • Open Access
434 Views
18 Pages

18 November 2025

The combination of antimicrobial agents with different mechanisms of action is an important step in the fight against drug-resistant microorganisms. In this study, the interaction of the lysozyme enzyme with ampicillin and colistin was investigated....

  • Article
  • Open Access
477 Views
15 Pages

12 November 2025

Early and accurate diagnosis of Alzheimer’s disease (AD) is critical for patient outcomes yet presents a significant clinical challenge. This study evaluates the effectiveness of four machine learning models—Logistic Regression, Random Fo...

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Biophysica - ISSN 2673-4125