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Neuroglia, Volume 4, Issue 2

2023 June - 4 articles

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Articles (4)

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Article

6 Citations

5,432 Views

17 Pages

Focused Ultrasound-Mediated Blood–Brain Barrier Opening Best Promotes Neuroimmunomodulation through Brain Macrophage Redistribution

Alina R. Kline-Schoder,
Rebecca L. Noel,
Hemali Phatnani,
Vilas Menon and
Elisa E. Konofagou

Neuroglia2023, 4(2), 141-157;https://doi.org/10.3390/neuroglia4020010

31 May 2023

Neuroimmunomodulation is a promising form of drug-free treatment for neurological diseases ranging from Alzheimer’s disease to depression. The evidence supporting the efficacy of focused ultrasound (FUS) neuroimmunomodulation is encouraging; ho...

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Perspective

3 Citations

5,989 Views

22 Pages

The Role of Lactylation in Mental Illness: Emphasis on Microglia

Adonis Sfera,
Carolina Klein,
Johnathan J. Anton,
Zisis Kozlakidis and
Christina V. Andronescu

Neuroglia2023, 4(2), 119-140;https://doi.org/10.3390/neuroglia4020009

16 May 2023

A paradigm shift is currently taking place in the etiopathogenesis of neuropsychiatric disorders as immunometabolism is replacing the earlier neurotransmitter model. According to the new concept, cellular bioenergetics drives information processing i...

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Article

5 Citations

2,853 Views

17 Pages

Q1VA, a Synthetic Chalcone, Induces Apoptosis and Decreases Invasion on Primary Culture of Human Glioblastoma

Anderson Togni,
Tetsade Piermartiri,
Luiz Felipe Schmitz de Souza,
Louise Domeneghi Chiaradia Delatorre,
Ricardo José Nunes,
Carla Inês Tasca and
Cláudia Beatriz Nedel

Neuroglia2023, 4(2), 102-118;https://doi.org/10.3390/neuroglia4020008

30 April 2023

Glioblastoma (GBM) is the most commonly occurring type of primary tumor of the central nervous system (CNS) and is considered the worst type of glioma. Despite the current standard treatment for newly diagnosed GBM, which involves surgery followed by...

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Review

7 Citations

6,809 Views

15 Pages

Convergence of Pro-Stress and Pro-Inflammatory Signaling in the Central Noradrenergic System: Implications for Mood and Anxiety Disorders

Arthur Anthony A. Reyes and
Daniel J. Chandler

Neuroglia2023, 4(2), 87-101;https://doi.org/10.3390/neuroglia4020007

29 April 2023

Mood and anxiety disorders are heterogeneous psychiatric diagnoses affecting millions. While the disease etiology is complex, various risk factors have been identified, such as stress. Stress is a neuroendocrine physiologic response to a stressor tha...

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