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Bio-Catalysis and Biomedical Perspectives of Magnetic Nanoparticles as Versatile Carriers

1
School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China
2
Bio-X Institute, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, China
3
School of Chemistry & Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, Shanghai 200240, China
4
Tecnologico de Monterrey, School of Engineering and Sciences, Campus Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L. CP 64849, Mexico
*
Authors to whom correspondence should be addressed.
Magnetochemistry 2019, 5(3), 42; https://doi.org/10.3390/magnetochemistry5030042
Received: 9 May 2019 / Revised: 24 June 2019 / Accepted: 27 June 2019 / Published: 2 July 2019
(This article belongs to the Special Issue Magnetic Nanoparticles)
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PDF [3932 KB, uploaded 2 July 2019]
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Abstract

In recent years, magnetic nanoparticles (MNPs) have gained increasing attention as versatile carriers because of their unique magnetic properties, biocatalytic functionalities, and capabilities to work at the cellular and molecular level of biological interactions. Moreover, owing to their exceptional functional properties, such as large surface area, large surface-to-volume ratio, and mobility and high mass transference, MNPs have been employed in several applications in different sectors such as supporting matrices for enzymes immobilization and controlled release of drugs in biomedicine. Unlike non-magnetic carriers, MNPs can be easily separated and recovered using an external magnetic field. In addition to their biocompatible microenvironment, the application of MNPs represents a remarkable green chemistry approach. Herein, we focused on state-of-the-art two majorly studied perspectives of MNPs as versatile carriers for (1) matrices for enzymes immobilization, and (2) matrices for controlled drug delivery. Specifically, from the applied perspectives of magnetic nanoparticles, a series of different applications with suitable examples are discussed in detail. The second half is focused on different metal-based magnetic nanoparticles and their exploitation for biomedical purposes. View Full-Text
Keywords: green chemistry; magnetic nanoparticles; enzyme immobilization; controlled drug delivery; supporting materials green chemistry; magnetic nanoparticles; enzyme immobilization; controlled drug delivery; supporting materials
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Bilal, M.; Mehmood, S.; Rasheed, T.; Iqbal, H.M.N. Bio-Catalysis and Biomedical Perspectives of Magnetic Nanoparticles as Versatile Carriers. Magnetochemistry 2019, 5, 42.

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