Review Reports
- Bhoomi Dave1,2,
- Monica Patel1 and
- Karanjit S. Kooner1,4,*
- et al.
Reviewer 1: Mohammadreza Aghamirsalim Reviewer 2: Anonymous Reviewer 3: Anonymous
Round 1
Reviewer 1 Report
Comments and Suggestions for AuthorsI found this manuscripg very intersting manuscript and this systematic review was siutabla for publication .
Author Response
Thank you so much for your comments. We appreciate your kind remarks and your approval of our manuscript.
Reviewer 2 Report
Comments and Suggestions for Authorssee attached
Comments for author File: 
Comments.pdf
The English is OK.
Author Response
We really appreciate your comments! Please see the attachment.
Author Response File: Author Response.pdf
Reviewer 3 Report
Comments and Suggestions for AuthorsThis is an excellent review describing techniques and pitfalls of glaucoma surgical treatments. Having myself had a past interest in this field, I may only suggest a further addition to their list of potential innovative treatments to control filtration surgery. The work published in 2023 by Minnelli et al. (DOI: 10.3390/ph16040594) described the effects of Meldonium on the control of IOP and simultaneously interfering with the fibrotic reaction after glaucoma filtration surgery (GFS). Therefore, the use of meldonium as eye drops in a trans-epithelial formulation with nanomicelles might represent a novel conservative treatment after GFS, prolonging the hypotonizing effects of the surgical intervention and adding a further relevant hypotonizing effect, with minimal risk of doping effects in treated patients.
Author Response
Thank you so much for your comments. We appreciate your kind remarks.