Next Article in Journal
Electrochemical Carbon Dioxide Reduction in Methanol at Cu and Cu2O-Deposited Carbon Black Electrodes
Previous Article in Journal
Multisensory Gas Chromatography for Field Analysis of Complex Gaseous Mixtures
Article Menu
Issue 1 (March) cover image

Export Article

Open AccessArticle

Application of Mathematical Modelling to Reducing and Minimising Energy Requirement for Oxygen Transfer in Batch Stirred Tank Bioreactors

Process & Chemical Engineering, School of Engineering, University College Cork, Cork T12YT20, Ireland
*
Author to whom correspondence should be addressed.
ChemEngineering 2019, 3(1), 14; https://doi.org/10.3390/chemengineering3010014
Received: 27 September 2018 / Revised: 20 November 2018 / Accepted: 30 January 2019 / Published: 3 February 2019
  |  
PDF [4382 KB, uploaded 3 February 2019]
  |  

Abstract

In this study, microbial kinetic and oxygen transfer modelling coupled with energy analysis was applied to investigate how manipulation and control of agitator power input and air flowrate can reduce and minimise the total energy requirement in a batch aerobic bioprocess subject to constraints. The study showed that major energy savings can be made by appropriate selection of these variables and how they are controlled throughout a bioprocess. In many bioprocesses, the oxygen concentration in the liquid is controlled at a constant value. This may be achieved by maintaining the agitator power at a constant value and varying the air flowrate or vice versa, or by continuously varying both. The modelling showed that the minimum or near-minimum total energy requirement occurred when operating at the onset of impeller flooding throughout the bioprocess by continuously varying both impeller power and air flowrate over the bioprocess time. Operating at the onset of flooding may not be practical to implement in practice. However, the minimum energy can be approached by dividing the bioprocess time into a small number of time segments with appropriately chosen constant agitator powers and varying the air flowrate within each segment. This is much more practical to implement. View Full-Text
Keywords: energy efficiency; aerobic bioprocess; batch stirred tank bioreactor; mathematical modelling energy efficiency; aerobic bioprocess; batch stirred tank bioreactor; mathematical modelling
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Fitzpatrick, J.J.; Gloanec, F.; Michel, E.; Blondy, J.; Lauzeral, A. Application of Mathematical Modelling to Reducing and Minimising Energy Requirement for Oxygen Transfer in Batch Stirred Tank Bioreactors. ChemEngineering 2019, 3, 14.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
ChemEngineering EISSN 2305-7084 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top