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Article

Comparative Reactive Oxygen Species (ROS) Content among Various Flavored Disposable Vape Bars, including Cool (Iced) Flavored Bars

Department of Environmental Medicine, University of Rochester Medical Center, Box 850, 601 Elmwood Avenue, Rochester, NY 14642, USA
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Author to whom correspondence should be addressed.
Academic Editors: Andrzej Sobczak and Leon Kośmider
Toxics 2021, 9(10), 235; https://doi.org/10.3390/toxics9100235
Received: 3 August 2021 / Revised: 13 September 2021 / Accepted: 16 September 2021 / Published: 25 September 2021
(This article belongs to the Special Issue Advantages and Disadvantages of Electronic Cigarettes)
Studies have shown that aerosols generated from flavored e-cigarettes contain Reactive Oxygen Species (ROS), promoting oxidative stress-induced damage within pulmonary cells. Our lab investigated the ROS content of e-cigarette vapor generated from disposable flavored e-cigarettes (vape bars) with and without nicotine. Specifically, we analyzed vape bars belonging to multiple flavor categories (Tobacco, Minty Fruit, Fruity, Minty/Cool (Iced), Desserts, and Drinks/Beverages) manufactured by various vendors and of different nicotine concentrations (0–6.8%). Aerosols from these vape bars were generated via a single puff aerosol generator; these aerosols were then individually bubbled through a fluorogenic solution to semi-quantify ROS generated by these bars in H2O2 equivalents. We compared the ROS levels generated by each vape bar as an indirect determinant of their potential to induce oxidative stress. Our results showed that ROS concentration (μM) within aerosols produced from these vape bars varied significantly among different flavored vape bars and identically flavored vape bars with varying nicotine concentrations. Furthermore, our results suggest that flavoring chemicals and nicotine play a differential role in generating ROS production in vape bar aerosols. Our study provides insight into the differential health effects of flavored vape bars, in particular cool (iced) flavors, and the need for their regulation. View Full-Text
Keywords: vaping; ENDS; disposable e-cigarettes; vape bars; flavoring; flavoring chemicals; reactive oxygen species (ROS); disposables; oxidative stress vaping; ENDS; disposable e-cigarettes; vape bars; flavoring; flavoring chemicals; reactive oxygen species (ROS); disposables; oxidative stress
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MDPI and ACS Style

Yogeswaran, S.; Muthumalage, T.; Rahman, I. Comparative Reactive Oxygen Species (ROS) Content among Various Flavored Disposable Vape Bars, including Cool (Iced) Flavored Bars. Toxics 2021, 9, 235. https://doi.org/10.3390/toxics9100235

AMA Style

Yogeswaran S, Muthumalage T, Rahman I. Comparative Reactive Oxygen Species (ROS) Content among Various Flavored Disposable Vape Bars, including Cool (Iced) Flavored Bars. Toxics. 2021; 9(10):235. https://doi.org/10.3390/toxics9100235

Chicago/Turabian Style

Yogeswaran, Shaiesh, Thivanka Muthumalage, and Irfan Rahman. 2021. "Comparative Reactive Oxygen Species (ROS) Content among Various Flavored Disposable Vape Bars, including Cool (Iced) Flavored Bars" Toxics 9, no. 10: 235. https://doi.org/10.3390/toxics9100235

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