Targeted Contrast Agents for Molecular MRI
AbstractMolecular magnetic resonance imaging (MRI) provides information non-invasively at cellular and molecular levels, for both early diagnosis and monitoring therapeutic follow-up. This imaging technique requires the development of a new class of contrast agents, which signal changes (typically becomes enhanced) when in presence of the cellular or molecular process to be evaluated. Even if molecular MRI has had a prominent role in the advances in medicine over the past two decades, the large majority of the developed probes to date are still in preclinical level, or eventually in phase I or II clinical trials. The development of novel imaging probes is an emergent active research domain. This review focuses on gadolinium-based specific-targeted contrast agents, providing rational design considerations and examples of the strategies recently reported in the literature. View Full-Text
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Lacerda, S. Targeted Contrast Agents for Molecular MRI. Inorganics 2018, 6, 129.
Lacerda S. Targeted Contrast Agents for Molecular MRI. Inorganics. 2018; 6(4):129.Chicago/Turabian Style
Lacerda, Sara. 2018. "Targeted Contrast Agents for Molecular MRI." Inorganics 6, no. 4: 129.
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