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Zerumbone and Kaempferol Derivatives from the Rhizomes of Zingiber montanum (J. Koenig) Link ex A. Dietr. from Bangladesh

1
Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan
2
Program for Leading Graduate Schools, Health Life Science: Interdisciplinary and Glocal Oriented (HIGO) Program, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan
*
Author to whom correspondence should be addressed.
Separations 2019, 6(2), 31; https://doi.org/10.3390/separations6020031
Received: 10 May 2019 / Revised: 29 May 2019 / Accepted: 5 June 2019 / Published: 17 June 2019
(This article belongs to the Special Issue Extraction and Isolation of Natural Products)
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Abstract

Zingiber montanum (J. Koenig) Link ex A. Dietr. (Zingiberaceae) is known as “Banada” in Bangladesh, and the rhizomes are frequently used in traditional medicines for the treatment of constipation, dyspepsia, flatulence, stomach bloating, and as mosquito repellant. In this study, dried rhizomes were extracted successively with 95% and 50% ethanol and the combined extract was then subjected to various column chromatographic methods to isolate one sesquiterpenoid derivative, zerumbone (1) and five kaempferol derivatives, i.e., kaempferol 3-O-methyl ether (2), kaempferol 3-O-α-rhamnopyranoside (3), kaempferol 3-O-α-(4”-O-acetyl)rhamnopyranoside (4), kaempferol 3-O-α-(3”-O-acetyl)rhamnopyranoside (5), and kaempferol 3-O-α-(3”,4”-di-O-acetyl)rhamnopyranoside (6). All compounds except 1 were isolated for the first time from the title plant. View Full-Text
Keywords: Zingiber montanum; Zingiberaceae; zerumbone; flavonoids; kaempferol Zingiber montanum; Zingiberaceae; zerumbone; flavonoids; kaempferol
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Hassan, M.M.; Adhikari-Devkota, A.; Imai, T.; Devkota, H.P. Zerumbone and Kaempferol Derivatives from the Rhizomes of Zingiber montanum (J. Koenig) Link ex A. Dietr. from Bangladesh. Separations 2019, 6, 31.

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