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Proteomes, Volume 7, Issue 3

2019 September - 5 articles

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Articles (5)

  • Article
  • Open Access
14 Citations
4,145 Views
14 Pages

Towards Understanding Non-Infectious Growth-Rate Retardation in Growing Pigs

  • Ana M. Gutiérrez,
  • Juan Sotillo,
  • Sarah Schlosser,
  • Karin Hummel and
  • Ingrid Miller

11 September 2019

For growth-rate retardation in commercial growing pigs suffering from non-infectious diseases, no biomarker is available for early detection and prevention of the condition or for the diagnosis of affected animals. The point in question is that the...

  • Article
  • Open Access
21 Citations
7,085 Views
18 Pages

Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer’s Disease

  • Lenora Higginbotham,
  • Eric B. Dammer,
  • Duc M. Duong,
  • Erica Modeste,
  • Thomas J. Montine,
  • James J. Lah,
  • Allan I. Levey and
  • Nicholas T. Seyfried

Previous systems-based proteomic approaches have characterized alterations in protein co-expression networks of unfractionated asymptomatic (AsymAD) and symptomatic Alzheimer’s disease (AD) brains. However, it remains unclear how sample fractionation...

  • Feature Paper
  • Review
  • Open Access
35 Citations
15,647 Views
19 Pages

What is Normalization? The Strategies Employed in Top-Down and Bottom-Up Proteome Analysis Workflows

  • Matthew B. O’Rourke,
  • Stephanie E. L. Town,
  • Penelope V. Dalla,
  • Fiona Bicknell,
  • Naomi Koh Belic,
  • Jake P. Violi,
  • Joel R. Steele and
  • Matthew P. Padula

The accurate quantification of changes in the abundance of proteins is one of the main applications of proteomics. The maintenance of accuracy can be affected by bias and error that can occur at many points in the experimental process, and normalizat...

  • Editorial
  • Open Access
11 Citations
5,200 Views
4 Pages

Extracellular vesicles (EVs) have recently emerged as an intercellular communication system that plays an important role in health and becomes dysfunctional in disease [...]

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Proteomes - ISSN 2227-7382