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Open AccessReview

Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities

1
Departament of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmacy, Nicolae Testemitanu SUMPh, 66 Mălina Mică Street, MD-2025 Chisinau, Moldova
2
Scientific Center of Medicines, Faculty of Pharmacy, Nicolae Testemitanu SUMPh, 66 Mălina Mică Street, MD-2025 Chisinau, Moldova
3
Departament of Pharmaceutical and Toxicological Chemistry, Faculty of Pharmacy, Nicolae Testemitanu SUMPh, 66 Mălina Mică Street, MD-2025 Chisinau, Moldova
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Department of Pharmaceutical Botany and Cell Biology, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, 6 Traian Vuia Street, Sector 2, 020956 Bucharest, Romania
*
Author to whom correspondence should be addressed.
Denotes equal contribution.
Biomolecules 2020, 10(12), 1619; https://doi.org/10.3390/biom10121619
Received: 13 October 2020 / Revised: 24 November 2020 / Accepted: 26 November 2020 / Published: 30 November 2020
(This article belongs to the Collection Pharmacology of Medicinal Plants)
Solidago virgaurea L. (European goldenrod, Woundwort), Asteraceae, is a familiar medicinal plant in Europe and other parts of the world, widely used and among the most researched species from its genus. The aerial parts of European goldenrod have long been used for urinary tract conditions and as an anti-inflammatory agent in the traditional medicine of different peoples. Its main chemical constituents are flavonoids (mainly derived from quercetin and kaempferol), C6-C1 and C6-C3 compounds, terpenes (mostly from the essential oil), and a large number of saponin molecules (mainly virgaureasaponins and solidagosaponins). Published research on its potential activities is critically reviewed here: antioxidant, anti-inflammatory, analgesic, spasmolitic, antihypertensive, diuretic, antibacterial, antifungal, antiparasite, cytotoxic and antitumor, antimutagenic, antiadipogenic, antidiabetic, cardioprotective, and antisenescence. The evidence concerning its potential benefits is mainly derived from non-clinical studies, some effects are rather modest, whereas others are more promising, but need more confirmation in both non-clinical models and clinical trials. View Full-Text
Keywords: Solidago vigaurea L.; European goldenrod; asteraceae; ethnomedicinal; phytochemistry; distribution; pharmacological activity Solidago vigaurea L.; European goldenrod; asteraceae; ethnomedicinal; phytochemistry; distribution; pharmacological activity
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MDPI and ACS Style

Fursenco, C.; Calalb, T.; Uncu, L.; Dinu, M.; Ancuceanu, R. Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities. Biomolecules 2020, 10, 1619. https://doi.org/10.3390/biom10121619

AMA Style

Fursenco C, Calalb T, Uncu L, Dinu M, Ancuceanu R. Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities. Biomolecules. 2020; 10(12):1619. https://doi.org/10.3390/biom10121619

Chicago/Turabian Style

Fursenco, Cornelia; Calalb, Tatiana; Uncu, Livia; Dinu, Mihaela; Ancuceanu, Robert. 2020. "Solidago virgaurea L.: A Review of Its Ethnomedicinal Uses, Phytochemistry, and Pharmacological Activities" Biomolecules 10, no. 12: 1619. https://doi.org/10.3390/biom10121619

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