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Review

Major Nutritional Metabolic Alterations Influencing the Reproductive System of Postpartum Dairy Cows

1
National Engineering Laboratory for Animal Breeding, Key Laboratory of Animal Genetics, Breeding and Reproduction, College of Animal Sciences and Technology, China Agricultural University, Beijing 100193, China
2
State Key Laboratory of Animal Nutrition, College of Animal Sciences and Technology, China Agricultural University, Beijing 100193, China
3
Faculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan 29220, Pakistan
4
Embryo Biotechnology and Reproduction Laboratory, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, China
*
Author to whom correspondence should be addressed.
Academic Editor: Jennifer W. Hill
Metabolites 2022, 12(1), 60; https://doi.org/10.3390/metabo12010060
Received: 2 December 2021 / Revised: 6 January 2022 / Accepted: 8 January 2022 / Published: 10 January 2022
(This article belongs to the Special Issue Metabolism and Reproduction)
Early successful conception of postpartum dairy cows is crucial in determining the optimum reproductive efficiency and profitability in modern dairy farming. Due to the inherent high production potential of modern dairy cows, the extra stress burden of peri-parturient events, and associated endocrine and metabolic changes causes negative energy balance (NEBAL) in postpartum cows. The occurrence of NEBAL is associated with excessive fat mobilization in the form of non-esterified fatty acids (NEFAs). The phenomenon of NEFA mobilization furthers with occurrence of ketosis and fatty liver in postpartum dairy cows. High NEFAs and ketones are negatively associated with health and reproductive processes. An additional burden of hypocalcemia, ruminal acidosis, and high protein metabolism in postpartum cows presents further consequences for health and reproductive performance of postpartum dairy cows. This review intends to comprehend these major nutritional metabolic alterations, their mechanisms of influence on the reproduction process, and relevant mitigation strategies. View Full-Text
Keywords: dairy cow; parturition; fertility; metabolic disorders; reproductive performance; ketosis; milk fever; fatty liver dairy cow; parturition; fertility; metabolic disorders; reproductive performance; ketosis; milk fever; fatty liver
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MDPI and ACS Style

Sammad, A.; Khan, M.Z.; Abbas, Z.; Hu, L.; Ullah, Q.; Wang, Y.; Zhu, H.; Wang, Y. Major Nutritional Metabolic Alterations Influencing the Reproductive System of Postpartum Dairy Cows. Metabolites 2022, 12, 60. https://doi.org/10.3390/metabo12010060

AMA Style

Sammad A, Khan MZ, Abbas Z, Hu L, Ullah Q, Wang Y, Zhu H, Wang Y. Major Nutritional Metabolic Alterations Influencing the Reproductive System of Postpartum Dairy Cows. Metabolites. 2022; 12(1):60. https://doi.org/10.3390/metabo12010060

Chicago/Turabian Style

Sammad, Abdul, Muhammad Zahoor Khan, Zaheer Abbas, Lirong Hu, Qudrat Ullah, Yajing Wang, Huabin Zhu, and Yachun Wang. 2022. "Major Nutritional Metabolic Alterations Influencing the Reproductive System of Postpartum Dairy Cows" Metabolites 12, no. 1: 60. https://doi.org/10.3390/metabo12010060

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