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Review

Neurocosmetics in Skincare—The Fascinating World of Skin–Brain Connection: A Review to Explore Ingredients, Commercial Products for Skin Aging, and Cosmetic Regulation

1
Dipartimento di Chimica, Università degli Studi “Aldo Moro” di Bari, Via Orabona, 4-70126 Bari, Italy
2
Consiglio Nazionale delle Ricerche CNR-IPCF, UOS Bari, Via Orabona, 4-70126 Bari, Italy
*
Authors to whom correspondence should be addressed.
Academic Editor: Leonhard Zastrow
Cosmetics 2021, 8(3), 66; https://doi.org/10.3390/cosmetics8030066
Received: 9 June 2021 / Revised: 28 June 2021 / Accepted: 12 July 2021 / Published: 16 July 2021
The “modern” cosmetology industry is focusing on research devoted to discovering novel neurocosmetic functional ingredients that could improve the interactions between the skin and the nervous system. Many cosmetic companies have started to formulate neurocosmetic products that exhibit their activity on the cutaneous nervous system by affecting the skin’s neuromediators through different mechanisms of action. This review aims to clarify the definition of neurocosmetics, and to describe the features of some functional ingredients and products available on the market, with a look at the regulatory aspect. The attention is devoted to neurocosmetic ingredients for combating skin stress, explaining the stress pathways, which are also correlated with skin aging. “Neuro-relaxing” anti-aging ingredients derived from plant extracts and neurocosmetic strategies to combat inflammatory responses related to skin stress are presented. Afterwards, the molecular basis of sensitive skin and the suitable neurocosmetic ingredients to improve this problem are discussed. With the aim of presenting the major application of Botox-like ingredients as the first neurocosmetics on the market, skin aging is also introduced, and its theory is presented. To confirm the efficacy of the cosmetic products on the market, the concept of cosmetic claims is discussed. View Full-Text
Keywords: neurocosmetics; neurocosmetic ingredients; skin care cosmetics; skin aging; skin stress; anti-wrinkle; cosmetics; sensitive skin; Botox-like ingredients neurocosmetics; neurocosmetic ingredients; skin care cosmetics; skin aging; skin stress; anti-wrinkle; cosmetics; sensitive skin; Botox-like ingredients
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MDPI and ACS Style

Rizzi, V.; Gubitosa, J.; Fini, P.; Cosma, P. Neurocosmetics in Skincare—The Fascinating World of Skin–Brain Connection: A Review to Explore Ingredients, Commercial Products for Skin Aging, and Cosmetic Regulation. Cosmetics 2021, 8, 66. https://doi.org/10.3390/cosmetics8030066

AMA Style

Rizzi V, Gubitosa J, Fini P, Cosma P. Neurocosmetics in Skincare—The Fascinating World of Skin–Brain Connection: A Review to Explore Ingredients, Commercial Products for Skin Aging, and Cosmetic Regulation. Cosmetics. 2021; 8(3):66. https://doi.org/10.3390/cosmetics8030066

Chicago/Turabian Style

Rizzi, Vito, Jennifer Gubitosa, Paola Fini, and Pinalysa Cosma. 2021. "Neurocosmetics in Skincare—The Fascinating World of Skin–Brain Connection: A Review to Explore Ingredients, Commercial Products for Skin Aging, and Cosmetic Regulation" Cosmetics 8, no. 3: 66. https://doi.org/10.3390/cosmetics8030066

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