Evaluation of the Filming and Protective Properties of a New Trehalose and Ceramides Based Ingredient
by
Letteria Greco 1,*
, Salviana Ullo 2,*, Luigi Rigano 3, Marco Fontana 1, Enzo Berardesca 4 and Norma Cameli 4
Letteria Greco 1,*, Salviana Ullo 2,*, Luigi Rigano 3, Marco Fontana 1, Enzo Berardesca 4 and Norma Cameli 4
1
Sinerga Group, Via della Pacciarna 67, 21050 Gorla Maggiore, VA, Italy
2
Sinerga SPA, Via della Pacciarna 67, 21050 Gorla Maggiore, VA, Italy
3
ISPE, Institute of Skin and Product Evaluation, Via Giuseppe Bruschetti, 1, 20125 Milano, MI, Italy
4
Istituto Dermatologico S. Maria e S. Gallicano, IRRCS Via Chianesi 53, 00144 Roma, Italy
*
Authors to whom correspondence should be addressed.
Cosmetics 2019, 6(4), 62; https://doi.org/10.3390/cosmetics6040062
Received: 16 September 2019 / Revised: 18 October 2019 / Accepted: 21 October 2019 / Published: 25 October 2019
(This article belongs to the Special Issue Cosmetics: Feature Papers)
The aim of this study is showing the filming and skin barrier protective properties of a new ingredient based on ceramides and trehalose and carried in lipophilic vesicles composed of lecithin and cholesterol (or phytosterols). Through an in vivo study, the restructuring and hydrating properties of this trehalose and ceramides compound have been evaluated. Furthermore, this new ingredient has been used in a topical formulation for atopic dermatitis, proving to be effective in the alterations of skin barrier. This evidence makes it an interesting ingredient for topical dermatological compositions in the treatment of dermatitis and all manifestations correlated to these skin disorders, such as edema, swelling, rash, redness, and itching. Its soothing and protective action against the painful and annoying symptoms like those given by dermatitis makes this trehalose and ceramides based ingredient for topical use.
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Keywords:
trehalose; ceramides; lecithin; skin disorders; dermatitis; xerosis
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MDPI and ACS Style
Greco, L.; Ullo, S.; Rigano, L.; Fontana, M.; Berardesca, E.; Cameli, N. Evaluation of the Filming and Protective Properties of a New Trehalose and Ceramides Based Ingredient. Cosmetics 2019, 6, 62.
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