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Cosmetics 2018, 5(4), 70;

Preparation of Innovative Skin Compatible Films to Release Polysaccharides for Biobased Beauty Masks

Department of Civil and Industrial Engineering, University of Pisa, 56122 Pisa, Italy
Interuniversity National Consortium of Materials Science and Technology (INSTM), 50121 Florence, Italy
Department of Mental Health and Physics and Preventive Medicine, Unit of Dermatology, University of Campania “Luigi Vanvitelli”, 80100 Naples, Italy
Department of Experimental Medicine, University of Campania“Luigi Vanvitelli”, 80138 Naples, Italy
Author to whom correspondence should be addressed.
Received: 31 October 2018 / Revised: 27 November 2018 / Accepted: 28 November 2018 / Published: 1 December 2018
PDF [5544 KB, uploaded 11 December 2018]


The preparation and selection of biobased materials compatible with skin is essential for producing innovative and highly eco-friendly beauty masks. The use of a commercial elastomeric poly(hydroxyalkanoate) and starch was fundamental to select materials for bioplastic films with the necessary resistance in wet conditions, skin compatibility and capacity for a fast release of polysaccharides and similar active and functional molecules. Micrometric calcium carbonate was also used to control the stickiness of film during moulding. Starch release in water was investigated by gravimetric and infrared analyses. The compatibility with skin was investigated via two different in vitro tests based on human keratinocytes and human mesenchymal stromal cells. The materials were highly cytocompatible with skin, enabled immune modulation by keratinocytes and starch release in water up to 49% by weight in 30 min. These outcomes are a good starting point for boosting the production of biobased and biodegradable beauty masks, thus decreasing the impact onto environment of cosmetic products that are currently still mainly produced using petrol-based substrates. View Full-Text
Keywords: biopolymers; skin; cosmetic; beauty mask; mesenchymal stromal cells; keratinocytes biopolymers; skin; cosmetic; beauty mask; mesenchymal stromal cells; keratinocytes

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Coltelli, M.-B.; Danti, S.; Trombi, L.; Morganti, P.; Donnarumma, G.; Baroni, A.; Fusco, A.; Lazzeri, A. Preparation of Innovative Skin Compatible Films to Release Polysaccharides for Biobased Beauty Masks. Cosmetics 2018, 5, 70.

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