Photoprotective Efficacy of the Association of Rosmarinic Acid 0.1% with Ethylhexyl Methoxycinnamate and Avobenzone
Abstract
:1. Introduction
2. Materials and Methods
2.1. Samples
2.2. In Vitro Photoprotective Efficacy and Photostability Assay
2.3. In Vivo Sun Protection Factor (SPF)
2.4. Statistical Analyses
3. Results and Discussion
4. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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Composition | Phase | Concentration (% w/w) | ||
---|---|---|---|---|
F1 | F2 | F3 | ||
Cetearyl alcohol (and) dicetyl phosphate (and) ceteareth-10 phosphate | O | 4.0 | 4.0 | 4.0 |
Isopropyl myristate | O | 5.0 | 5.0 | 5.0 |
Ethylhexyl methoxycinnamate | O | 10.0 | 10.0 | 10.0 |
Butil methoxydibenzoylmethane (avobenzone) | O | 5.0 | 2.5 | 5.0 |
Rosmarinic acid | F | - | 0.1 | 0.1 |
Glycerin | A | 5.0 | 5.0 | 5.0 |
Phenoxyethanol (and) methylparaben (and) butylparaben (and) ethylparaben (and) propylparaben (and) isobutylparaben | A | 0.75 | 0.75 | 0.75 |
Ammoniumacryloyldimethyltaurate/VPcopolymer | A | 1.0 | 1.0 | 1.0 |
Ethanol | F | 5.0 | 5.0 | 5.0 |
Purified water | A | q.s. 100.0 | q.s. 100.0 | q.s. 100.0 |
Samples | In Vitro SPF | Critical Wavelength (nm) |
---|---|---|
F1 | 12.00 ± 1.73 A | 382.67 ±0.58 C |
F2 | 15.67 ± 3.51 AB | 379.34 ±0.58 D |
F3 | 17.33 ± 0.58 B | 381.67 ±0.58 C |
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de Oliveira Bispo, M.; Morocho-Jácome, A.L.; Escudeiro, C.C.; Martinez, R.M.; de Oliveira Pinto, C.A.S.; Rosado, C.; Velasco, M.V.R.; Baby, A.R. Photoprotective Efficacy of the Association of Rosmarinic Acid 0.1% with Ethylhexyl Methoxycinnamate and Avobenzone. Cosmetics 2023, 10, 11. https://doi.org/10.3390/cosmetics10010011
de Oliveira Bispo M, Morocho-Jácome AL, Escudeiro CC, Martinez RM, de Oliveira Pinto CAS, Rosado C, Velasco MVR, Baby AR. Photoprotective Efficacy of the Association of Rosmarinic Acid 0.1% with Ethylhexyl Methoxycinnamate and Avobenzone. Cosmetics. 2023; 10(1):11. https://doi.org/10.3390/cosmetics10010011
Chicago/Turabian Stylede Oliveira Bispo, Maíra, Ana Lucía Morocho-Jácome, Cassiano Carlos Escudeiro, Renata Miliani Martinez, Claudinéia Aparecida Sales de Oliveira Pinto, Catarina Rosado, Maria Valéria Robles Velasco, and André Rolim Baby. 2023. "Photoprotective Efficacy of the Association of Rosmarinic Acid 0.1% with Ethylhexyl Methoxycinnamate and Avobenzone" Cosmetics 10, no. 1: 11. https://doi.org/10.3390/cosmetics10010011