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Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients

1
Graduate School of Industrial Science and Technology, Tokyo University of Science, Katsushika-ku, Tokyo 125-8585, Japan
2
International Center for Materials Nanoarchitectonics (WPI-MANA), National Institute for Materials Science (NIMS), Tsukuba, Ibaraki 305-0044, Japan
3
Graduate School of Pure and Applied Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8577, Japan
*
Author to whom correspondence should be addressed.
Fibers 2019, 7(5), 39; https://doi.org/10.3390/fib7050039
Received: 22 February 2019 / Revised: 19 April 2019 / Accepted: 22 April 2019 / Published: 1 May 2019
(This article belongs to the Special Issue Electrospun Polymer Nanofibers for Food and Health Applications)
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Abstract

Excellent water-absorbing nanofiber meshes were developed as a potential material for removing excess fluids from the blood of chronic renal failure patients toward a wearable blood purification system without requiring specialized equipment. The nanofiber meshes were successfully fabricated from poly(acrylic acid) (PAA) under various applied voltages by appropriately setting the electrospinning conditions. The electrospun PAA nanofibers were thermally crosslinked via heat treatment and then neutralized from their carboxylic acid form (PAA) to a sodium carboxylate form poly(sodium acrylate) (PSA). The PSA nanofiber meshes exhibited a specific surface area 393 times that of the PSA film. The PSA fiber meshes showed a much faster and higher swelling than its corresponding film, owing to the higher capillary forces from the fibers in addition to the water absorption of the PSA gel itself. The proposed PSA fibers have the potential to be utilized in a new approach to remove excess water from the bloodstream without requiring specialized equipment. View Full-Text
Keywords: water absorbing materials; nanofibers; electrospinning; poly(sodium acrylate); hemodialysis water absorbing materials; nanofibers; electrospinning; poly(sodium acrylate); hemodialysis
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Tsuge, M.; Takahashi, K.; Kurimoto, R.; Fulati, A.; Uto, K.; Kikuchi, A.; Ebara, M. Fabrication of Water Absorbing Nanofiber Meshes toward an Efficient Removal of Excess Water from Kidney Failure Patients. Fibers 2019, 7, 39.

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