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Open AccessCommunication

Formulation of Lipoprotein Microencapsulated Beadlets by Ionic Complexes in Algae-Based Carbohydrates

1
Research and Development, CENCIRA Agrofood Research and Innovation Centre, 400650 Cluj-Napoca, Romania
2
Department of Food Science, Life Science Institute, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Science, 400372 Cluj-Napoca, Romania
3
Nutrition and Public Health, University of Oradea, 410087 Oradea, Romania
*
Authors to whom correspondence should be addressed.
Coatings 2020, 10(3), 302; https://doi.org/10.3390/coatings10030302
Received: 28 February 2020 / Revised: 21 March 2020 / Accepted: 23 March 2020 / Published: 24 March 2020
The present study aims to produce sustained-release algae-based carbohydrate microbeadlets of lipoproteins rich-in carotenoids extracted from organic sea buckthorn fruits. β-carotene represented the major compound of the lipoproteins extracts. Emulsification and algae-based carbohydrates, such as sodium-alginate and kappa-carrageenan, provide an inert environment, allowing the embedded targeted bioactive compounds—lipoproteins rich in carotenoids in our case—to maintain greater biological activity and to have a better shelf life. Furthermore, the microbeadlets prepared from sodium-alginate–kappa-carrageenan (0.75%:0.75% w/v) crosslinked with calcium ions showing 90% encapsulation efficiency have been utilized in HPMC capsules using beadlets-in-a-capsule technology, to use as a delivery system for the finished product. The GI simulated tests performed under laboratory conditions suggested that the sodium-alginate–kappa–carrageenan combination could be useful for the formulation-controlled release of microbeadlets containing lipoproteins rich in carotenoids. View Full-Text
Keywords: lipoprotein; carbohydrate; beadlet; emulsion; release; HPMC; beadlet-in-a-capsule lipoprotein; carbohydrate; beadlet; emulsion; release; HPMC; beadlet-in-a-capsule
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Rusu, A.V.; Criste, F.L.; Mierliţă, D.; Socol, C.T.; Trif, M. Formulation of Lipoprotein Microencapsulated Beadlets by Ionic Complexes in Algae-Based Carbohydrates. Coatings 2020, 10, 302.

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