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Cannabinoids-Promising Antimicrobial Drugs or Intoxicants with Benefits?

Institute of Organic Chemistry, Technische Universität Braunschweig, Hagenring 30, D-38106 Braunschweig, Germany
Academic Editor: William N. Setzer
Antibiotics 2020, 9(6), 297; https://doi.org/10.3390/antibiotics9060297
Received: 11 May 2020 / Revised: 29 May 2020 / Accepted: 30 May 2020 / Published: 2 June 2020
(This article belongs to the Special Issue Antimicrobial Activity of Higher Plants)
Novel antimicrobial drugs are urgently needed to counteract the increasing occurrence of bacterial resistance. Extracts of Cannabis sativa have been used for the treatment of several diseases since ancient times. However, its phytocannabinoid constituents are predominantly associated with psychotropic effects and medical applications far beyond the treatment of infections. It has been demonstrated that several cannabinoids show potent antimicrobial activity against primarily Gram-positive bacteria including methicillin-resistant Staphylococcus aureus (MRSA). As first in vivo efficacy has been demonstrated recently, it is time to discuss whether cannabinoids are promising antimicrobial drug candidates or overhyped intoxicants with benefits. View Full-Text
Keywords: cannabinoids; antimicrobial drug; microbial resistance; methicillin-resistant Staphylococcus aureus (MRSA); broad-spectrum antibiotics; antibiofilm activity; persister cell killing cannabinoids; antimicrobial drug; microbial resistance; methicillin-resistant Staphylococcus aureus (MRSA); broad-spectrum antibiotics; antibiofilm activity; persister cell killing
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MDPI and ACS Style

Klahn, P. Cannabinoids-Promising Antimicrobial Drugs or Intoxicants with Benefits? Antibiotics 2020, 9, 297. https://doi.org/10.3390/antibiotics9060297

AMA Style

Klahn P. Cannabinoids-Promising Antimicrobial Drugs or Intoxicants with Benefits? Antibiotics. 2020; 9(6):297. https://doi.org/10.3390/antibiotics9060297

Chicago/Turabian Style

Klahn, Philipp. 2020. "Cannabinoids-Promising Antimicrobial Drugs or Intoxicants with Benefits?" Antibiotics 9, no. 6: 297. https://doi.org/10.3390/antibiotics9060297

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