Next Article in Journal
Ligand-Based Stability Changes in Duplex DNA Measured with a Microscale Electrochemical Platform
Previous Article in Journal
Specific and Generic Immunorecognition of Glycopeptide Antibiotics Promoted by Unique and Multiple Orientations of Hapten
Previous Article in Special Issue
Ex Vivo Raman Spectrochemical Analysis Using a Handheld Probe Demonstrates High Predictive Capability of Brain Tumour Status
Article Menu

Export Article

Open AccessArticle

Robust SERS Platforms Based on Annealed Gold Nanostructures Formed on Ultrafine Glass Substrates for Various (Bio)Applications

1
Light, Nanomaterials and Nanotechnology (L2N), FRE-CNRS 2019, Institute Charles Delaunay (ICD), University of Technology of Troyes, 12 Rue Marie Curie CS 42060, 10004 Troyes CEDEX, France
2
Dipartimento di Scienze Agroalimentari, Ambientali e Animali (DI4A), Università degli Studi di Udine, Via Sondrio 2/A, 33100 Udine, Italy
*
Author to whom correspondence should be addressed.
Biosensors 2019, 9(2), 53; https://doi.org/10.3390/bios9020053
Received: 14 February 2019 / Revised: 21 March 2019 / Accepted: 29 March 2019 / Published: 10 April 2019
(This article belongs to the Special Issue Spectroscopy-Based Biosensors)
  |  
PDF [2853 KB, uploaded 29 April 2019]
  |  

Abstract

In this study, stable gold nanoparticles (AuNPs) are fabricated for the first time on commercial ultrafine glass coverslips coated with gold thin layers (2 nm, 4 nm, 6 nm, and 8 nm) at 25 °C and annealed at high temperatures (350 °C, 450 °C, and 550 °C) on a hot plate for different periods of time. Such gold nanostructured coverslips were systematically tested via surface enhanced Raman spectroscopy (SERS) to identify their spectral performances in the presence of different concentrations of a model molecule, namely 1,2-bis-(4-pyridyl)-ethene (BPE). By using these SERS platforms, it is possible to detect BPE traces (10−12 M) in aqueous solutions in 120 s. The stability of SERS spectra over five weeks of thiol-DNA probe (2 µL) deposited on gold nano-structured coverslip is also reported. View Full-Text
Keywords: SERS on ultrafine solid supports; glass coverslips; BPE; thiol-DNA probe; annealed gold nanostructures SERS on ultrafine solid supports; glass coverslips; BPE; thiol-DNA probe; annealed gold nanostructures
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Zhou, L.; Poggesi, S.; Casari Bariani, G.; Mittapalli, R.; Adam, P.-M.; Manzano, M.; Ionescu, R.E. Robust SERS Platforms Based on Annealed Gold Nanostructures Formed on Ultrafine Glass Substrates for Various (Bio)Applications. Biosensors 2019, 9, 53.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Biosensors EISSN 2079-6374 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top