Impact of Chest Trauma and Overweight on Mortality and Outcome in Severely Injured Patients
Abstract
:1. Introduction
2. Experimental Section
2.1. Study Design and Inclusion Criteria
2.2. Injury Distribution and Injury Severity
2.3. In-Hospital Complications and Mortality
2.4. Body Mass Index (BMI)
2.5. Statistical Analysis
3. Results
3.1. Chest Trauma
3.2. Impact of BMI and Chest Trauma
4. Discussion
- Severe chest trauma was associated with prolonged treatment and in-hospital complications.
- Subgroup analysis revealed overweight to be an independent survival factor in patients with severe chest trauma. In contrast, this aspect was not proven for severely injured patients with only minor chest trauma.
5. Conclusions
Author Contributions
Funding
Conflicts of Interest
References
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Overall | Group I | Group II | p-Value | |
---|---|---|---|---|
Number of patients (n) | 338 | 137 | 201 | - |
Age (median 25/75-IQR) | 52 (36–68) | 49.0 (38–62) | 52 (34–72) | 0.175 |
Male (%) | 70 | 75 | 67 | 0.113 |
ISS (median 25/75-IQR) | 24 (17–29) | 27.0 (18–34) | 24 (17–25) | <0.001 |
AIS head (median 25/75-IQR) | 3.5 (0–4) | 1.0 (0–3) | 4.0 (3.0–5.0) | <0.001 |
BMI (median 25/75-IQR) | 25.1 (23–28) | 25.7 (24–28) | 24.8 (23–28) | 0.042 |
Underweight (n) | 30 | 13 | 17 | |
Normal weight (n) | 146 | 54 | 92 | |
Overweight (n) | 119 | 53 | 66 | |
Obesity (n) | 43 | 20 | 23 | |
MODS (%) | 26.3 | 30.3 | 20.1 | <0.001 |
Mortality (%) | 24.3 | 32.3 | 12.4 | <0.001 |
Duration of ventilation (h) (median 25/75-IQR) | 48 (2–258) | 70 (10–222) | 25 (0–287) | 0.022 |
Duration of ICU treatment (days) (median 25/75-IQR) | 11 (1–23) | 17 (9–29) | 6 (2–17) | <0.001 |
Length of stay (days) (median 25/75-IQR) | 16 (7–27) | 17 (10–29) | 14 (5–25) | 0.008 |
Regression Coefficient | Odds Ratio (OR) | 95% Confidence Interval (95%-CI) | p-Value | |
---|---|---|---|---|
Age (years) | 0.027 | 1.028 | 0.988–1.069 | 0.172 |
Gender (male) | −0.218 | 0.804 | 0.232–6.671 | 0.799 |
Overweight | −1.847 | 0.158 | 0.028–0.892 | 0.037 |
Obesity | 0.030 | 1.094 | 0.203–5.885 | 0.917 |
ISS (per point) | 0.057 | 1.059 | 0.989–1.133 | 0.102 |
AIS head | 0.600 | 1.822 | 1.102–3.013 | 0.019 |
Constant | −6.148 | − | − | <0.001 |
Regression Coefficient | Odds Ratio (OR) | 95% Confidence Interval (95%-CI) | p-Value | |
---|---|---|---|---|
Age (years) | 0.028 | 1.028 | 1.009–0.048 | 0.004 |
Gender (male) | 0.387 | 1.472 | 0.684–3.166 | 0.323 |
Overweight | −0.311 | 0.733 | 0.334–1.607 | 0.438 |
Obesity | −0.282 | 0.755 | 0.234–2.434 | 0.637 |
ISS (per point) | 0.068 | 1.071 | 1.023–1.120 | 0.003 |
AIS head | 0.341 | 1.407 | 1.096–1.806 | 0.007 |
Constant | −4.928 | - | - | 0.007 |
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Eckhardt, T.; Horst, K.; Störmann, P.; Bläsius, F.; Hofman, M.; Herren, C.; Kobbe, P.; Hildebrand, F.; Andruszkow, H. Impact of Chest Trauma and Overweight on Mortality and Outcome in Severely Injured Patients. J. Clin. Med. 2020, 9, 2752. https://doi.org/10.3390/jcm9092752
Eckhardt T, Horst K, Störmann P, Bläsius F, Hofman M, Herren C, Kobbe P, Hildebrand F, Andruszkow H. Impact of Chest Trauma and Overweight on Mortality and Outcome in Severely Injured Patients. Journal of Clinical Medicine. 2020; 9(9):2752. https://doi.org/10.3390/jcm9092752
Chicago/Turabian StyleEckhardt, Thurid, Klemens Horst, Philipp Störmann, Felix Bläsius, Martijn Hofman, Christian Herren, Philipp Kobbe, Frank Hildebrand, and Hagen Andruszkow. 2020. "Impact of Chest Trauma and Overweight on Mortality and Outcome in Severely Injured Patients" Journal of Clinical Medicine 9, no. 9: 2752. https://doi.org/10.3390/jcm9092752