Medial Thigh Lift with Tumescent Local Anesthesia: Advancing Outpatient Body Contouring
Abstract
1. Introduction
2. Materials and Methods
2.1. Study Design and Setting
2.2. Preoperative Evaluation and Consent
2.3. Patient Selection Criteria
- Presence of significant medial thigh skin laxity, either age-related or following massive weight loss;
- Stable body weight for at least 6 months prior to surgery;
- Body mass index (BMI) ≤ 35 kg/m2;
- American Society of Anesthesiologists (ASA) physical status I or II;
- Absence of active infections, uncontrolled comorbidities, or psychiatric disorders.
- ASA class ≥ III;
- Active smoking or smoking cessation < 4 weeks;
- BMI > 35 kg/m2;
- Active dermatological conditions in the surgical area;
- History of lower limb lymphedema;
- Non-compliance with postoperative protocols or unrealistic expectations.
2.4. Patient Subgroup Classification
2.5. Anesthetic Protocol
Tumescent Local Anesthesia Preparation
2.6. Infiltration Technique
2.7. Dosage and Safety Considerations
2.8. Surgical Technique
2.8.1. Preoperative Marking
2.8.2. Operative Procedure
2.8.3. Postoperative Care
2.9. Outcome Assessment Protocol
3. Results
3.1. Patient Demographics and Baseline Characteristics
3.2. Procedural Efficacy and Operative Outcomes
3.3. Intraoperative Anesthetic Tolerance
3.4. Postoperative Pain Management
3.5. Complications and Safety Profile
4. Discussion
4.1. Tumescent Local Anesthesia in Body Contouring
4.2. Comparison with Existing Literature
4.3. Technical Advantages of TLA
4.4. Complication Management and Safety Profile
4.5. Economic and Logistical Considerations
4.6. Study Limitations
4.7. Limitations
4.8. Clinical Implications
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
TLA | Tumescent Local Anesthesia |
GA | General Anesthesia |
BMI | Body Mass Index |
ASA | American Society of Anesthesiologists |
POD | Postoperative Day |
OR | Operative Room |
ECG | Electrocardiogram |
IV | Intravenous |
VTE | Venous Thromboembolism |
TXA | Tranexamic Acid |
HRQoL | Health-Related Quality of Life |
References
- Boeni, R.; Waechter-Gniadek, P.V. Safety of Tumescent Liposuction Under Local Anesthesia in 9002 Consecutive Patients. Dermatol. Surg. 2021, 47, e184–e187, Erratum in Dermatol. Surg. 2022, 48, 1267. https://doi.org/10.1097/DSS.0000000000003632. [Google Scholar] [CrossRef] [PubMed]
- Klein, J.A. Tumescent liposuction and improved postoperative care using tumescent liposuction garments. Dermatol. Clin. 1995, 13, 329–338. [Google Scholar] [CrossRef] [PubMed]
- Namias, A.; Kaplan, B. Tumescent anesthesia for dermatologic surgery. Cosmetic and noncosmetic procedures. Dermatol. Surg. 1998, 24, 755–758. [Google Scholar] [CrossRef] [PubMed]
- Klein, J.A. Tumescent technique for local anesthesia. West. J. Med. 1996, 164, 517. [Google Scholar] [PubMed]
- Gutowski, K.A. Tumescent analgesia in plastic surgery. Plast. Reconstr. Surg. 2014, 134, 50S–57S. [Google Scholar] [CrossRef] [PubMed]
- Hanke, C.; Dent, M. Tumescent anesthesia: A brief history regarding the evolution of tumescent solution. J. Drugs Dermatol. 2021, 20, 1283–1287. [Google Scholar] [CrossRef] [PubMed]
- Bolletta, A.; Dessy, L.A.; Fiorot, L.; Tronci, A.; Rusciani, A.; Ciudad, P.; Trignano, E. Sub-muscular breast augmentation using tumescent local anesthesia. Aesthetic Plast. Surg. 2019, 43, 7–13. [Google Scholar] [CrossRef] [PubMed]
- Tettamanzi, M.; Sanna, C.; Liperi, C.; Manconi, A.; Trignano, C.; Rubino, C.; Trignano, E. Outcomes of abdominoplasty in tumescent local anesthesia combined with subdural anesthesia. Aesthetic Plast. Surg. 2024, 48, 361–368. [Google Scholar] [CrossRef] [PubMed]
- Trignano, E.; Tettamanzi, M.; Liperi, C.; Beatrici, E.; Serra, P.L.; Trignano, C.; Rubino, C. Outcomes of intramuscular gluteal augmentation with implants using tumescent local anesthesia. Aesthetic Plast. Surg. 2023, 47, 1931–1938. [Google Scholar] [CrossRef] [PubMed]
- Tettamanzi, M.; Ziani, F.; Arrica, G.; Rodio, M.; Pili, N.; Rubino, C.; Trignano, E. Use of radiofrequency-assisted liposuction (BodyTite) for upper arms lifting. Aesthetic Plast. Surg. 2023, 47, 2495–2501. [Google Scholar] [CrossRef] [PubMed]
- Chia, C.T.; Theodorou, S.J.; Dayan, E.; Tabbal, G.; Del Vecchio, D. “Brazilian butt lift” under local anesthesia: A novel technique addressing safety concerns. Plast. Reconstr. Surg. 2018, 142, 1468–1475. [Google Scholar] [CrossRef] [PubMed]
- Tettamanzi, M.; Ziani, F.; Arrica, G.; Filigheddu, E.; Trignano, C.; Rubino, C.; Trignano, E. Optimizing gynecomastia correction surgery: Efficacy and safety of tumescent local anesthesia approach. Aesthetic Plast. Surg. 2024, 48, 5067–5073. [Google Scholar] [CrossRef] [PubMed]
- Kanjoor, J.R.; De Sousa, R.F.; Subramaniam, S. Propofol-dexmedetomidine total intravenous anesthesia with tumescent anesthesia in aesthetic surgery. Aesthetic Plast. Surg. 2025, 49, 4025–4033. [Google Scholar] [CrossRef] [PubMed]
- Mathes, D.W.; Kenkel, J.M. Current concepts in medial thighplasty. Clin. Plast. Surg. 2008, 35, 151–163. [Google Scholar] [CrossRef] [PubMed]
- Wollina, U.; Heinig, B.; Nowak, A. Treatment of elderly patients with advanced lipedema: A combination of laser-assisted liposuction, medial thigh lift, and lower partial abdominoplasty. Clin. Cosmet. Investig. Dermatol. 2014, 7, 35–42. [Google Scholar] [CrossRef] [PubMed]
- Ziani, F.; Tettamanzi, M.; Arrica, G.; Cuomo, R.; Filigheddu, E.; Trignano, C.; Liperi, C.; Rubino, C.; Trignano, E. Safe and Effective Augmentation Mastopexy with Tumescent Local Anesthesia: A Decade of Experience. J. Clin. Med. 2024, 13, 6057. [Google Scholar] [CrossRef] [PubMed]
- Arrica, G.; Ziani, F.; Tettamanzi, M.; Filigheddu, E.; Trignano, C.; Rubino, C.; Trignano, E. Advancing reduction mammaplasty surgery: Advancements and outcomes with tumescent local anaesthesia. Aesthetic Plast. Surg. 2025, 49, 1708–1714. [Google Scholar] [CrossRef] [PubMed]
- Habbema, L. Efficacy of tumescent local anesthesia with variable lidocaine concentration in 3430 consecutive cases of liposuction. J. Am. Acad. Dermatol. 2010, 62, 988–994. [Google Scholar] [CrossRef] [PubMed]
- Ostad, A.; Kageyama, N.; Moy, R.L. Tumescent anesthesia with a lidocaine dose of 55 mg/kg is safe for liposuction. Dermatol. Surg. 1996, 22, 921–927. [Google Scholar] [CrossRef] [PubMed]
- Hanke, C.; Dent, M. Beyond liposuction: Evolving applications for tumescent anesthesia. J. Drugs Dermatol. 2022, 21, 86–89. [Google Scholar] [CrossRef] [PubMed]
- Wang, A.; Grushchak, S.; Kaul, S.; Lee, P.K.; Feldman, J. Toxicity of infiltrative lidocaine in dermatologic surgery: Are current limits valid? Dermatol. Pract. Concept. 2021, 11, e2021120. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Lockwood, T.E. Fascial anchoring technique in medial thigh lifts. Plast. Reconstr. Surg. 1988, 82, 299–304. [Google Scholar] [CrossRef] [PubMed]
- Ciudad, P.; Kaciulyte, J.; Lo Torto, F.; Vargas, M.I.; Bustamante, A.; Chen, H.C.; Maruccia, M.; Zulueta, J.; Trignano, E.; Bolletta, A. The profunda artery perforator free flap for lower extremity reconstruction. Microsurgery 2022, 42, 13–21. [Google Scholar] [CrossRef] [PubMed]
- Bajwa, M.S.; Bashir, M.M.; Bajwa, M.H.; Iqbal, Z.; Salahuddin, M.A.; Hussain, A.; Shahzad, F. How long to wait after local infiltration anaesthesia: Systematic review. BJS Open 2023, 7, zrad089. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Tettamanzi, M.; Ziani, F.; Rodio, M.; Arrica, G.; Filigheddu, E.; Trignano, C.; Rubino, C.; Trignano, E. Retrospective Study on Optimizing Breast Augmentation Outcomes in Transgender Patients: A Comprehensive Analysis of Tumescent Local Anesthesia Technique. Int. Soc. Aesthetic Plast. Surg. 2024, 48, 3817–3824. [Google Scholar] [CrossRef] [PubMed]
- Rusciani, A.; Pietramaggiori, G.; Troccola, A.; Santoprete, S.; Rotondo, A.; Curinga, G. The outcome of primary subglandular breast augmentation using tumescent local anesthesia. Ann. Plast. Surg. 2016, 76, 13–17. [Google Scholar] [CrossRef] [PubMed]
- Trignano, E.; Beatrici, E.; Blessent, C.G.F.; Liperi, C.; Serra, P.L.; Trignano, C.; Rubino, C.; Tettamanzi, M. Letter to the Editor: Outcomes of Intramuscular Gluteal Augmentation with Implants Using Tumescent Local Anesthesia. Aesthetic Plast. Surg. 2024, 48, 3552–3553. [Google Scholar] [CrossRef] [PubMed]
- Barone, M.; Salzillo, R.; Amenta, A.; Brunetti, B.; Tenna, S.; Persichetti, P. Balancing Aesthetics and Scarring: Insights from Post-Bariatric Brachioplasty. Aesth. Plast. Surg. 2025, 1–7. [Google Scholar] [CrossRef] [PubMed]
- Sisti, A.; Huayllani, M.T.; Boczar, D.; Zerini, I.; Tassinari, J.; Brandi, C.; Grimaldi, L.; D’Aniello, C.; Nisi, G. Complications associated with medial thigh lift: A comprehensive literature review. J. Cutan. Aesthet. Surg. 2015, 8, 191–197. [Google Scholar] [CrossRef] [PubMed]
- Kilian, K.K.; Panayi, A.C.; Matar, D.Y.; Hamwi, C.; Bigdeli, A.K.; Kneser, U.; Vollbach, F.H. Similarity of seroma rate at the medial thigh following free flap harvesting or medial thigh lift: A systematic review and meta-analysis. JPRAS Open 2024, 40, 360–374. [Google Scholar] [CrossRef] [PubMed]
- Labardi, L.; Gentile, P.; Gigliotti, S.; Marianetti, M.; Colicchia, G.M.; Pascali, M.; Brinci, L.; Cervelli, V. Medial thighplasty: Horizontal and vertical procedures after massive weight loss. J. Cutan. Aesthet. Surg. 2012, 5, 20–25. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Albanese, R.; Blessent, C.G.F.; Tomaselli, F.; De Santis, G.; Pinto, V.; Pinelli, M.; Buccheri, E.M.; Tambasco, D. A comprehensive review of medial thighplasty: The role of liposuction in reducing complications and optimizing patient outcomes. J. Clin. Med. 2025, 4, 2426. [Google Scholar] [CrossRef] [PubMed]
- Di Pietro, V.; Colicchia, G.M.; Cervelli, V. Medial thigh contouring after massive weight loss: The liposuction-assisted medial thigh lift (LAMeT). J. Cutan. Aesthetic Surg. 2020, 13, 305–313. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
- Lalonde, D.; Martin, A. Tumescent local anesthesia for hand surgery: Improved results, cost effectiveness, and wide-awake patient satisfaction. Arch. Plast. Surg. 2014, 41, 312–316. [Google Scholar] [CrossRef] [PubMed]
- Romero, J.; Rodriguez-Taveras, J.; Diaz, J.C.; Lorente-Ros, M.; Braunstein, E.D.; Alviz, I.; Parides, M.; Haroun, M.W.; Papa, L.; Dave, K.; et al. Tumescent local anesthesia versus general anesthesia for subcutaneous implantable cardioverter-defibrillator implantation: A cost-effectiveness analysis. Heart Rhythm 2023, 20, 522–529. [Google Scholar] [CrossRef] [PubMed]
- Cigna, E.; Tarallo, M.; Bistoni, G.; Anniboletti, T.; Trignano, E.; Tortorelli, G.; Scuderi, N. Evaluation of polyurethane dressing with ibuprofen in the management of split-thickness skin graft donor sites. In Vivo 2009, 23, 983–986. [Google Scholar] [PubMed]
- Trignano, E.; Serra, P.L.; Pili, N.; Trignano, C.; Rubino, C. Hybrid breast augmentation: Our surgical approach and formula for preoperative assessment of fat graft volume. Gland. Surg. 2022, 11, 1604–1614. [Google Scholar] [CrossRef] [PubMed] [PubMed Central]
Patient ID | Age | BMI | ASA Status | Surgical Type | Liposuction | Laxity Cause | Complications | Revision Needed | Intraop Pain Rating | 12 Month Satisfaction | Smoke | Diabetes | PRS Grade |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P01 | 45 | 28 | I | Excision only | No | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 2 |
P02 | 36 | 24.5 | I | Excision only | No | Post-weight loss | Hypertrophic scar | No | Good | Very satisfied | no | no | 2 |
P03 | 43 | 27.5 | I | Excision + liposuction | Yes | Post-weight loss | Dog ear | Yes | Excellent | Very satisfied | no | no | 2 |
P04 | 51 | 29 | I | Excision only | No | Age | None | No | Excellent | Very satisfied | no | no | 2 |
P05 | 40 | 26 | I | Excision + liposuction | Yes | Post-weight loss | Wound dehiscence | No | Good | Very satisfied | yes | yes | 2 |
P06 | 38 | 25 | I | Excision + liposuction | Yes | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 2 |
P07 | 29 | 26 | I | Excision only | No | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 2 |
P08 | 33 | 25 | I | Excision + liposuction | Yes | Post-weight loss | Scar migration | No | Excellent | Very satisfied | no | no | 2 |
P09 | 58 | 33 | II | Excision + liposuction | Yes | Age | None | No | Excellent | Very satisfied | no | no | 2 |
P10 | 36 | 31 | II | Excision only | No | Post-weight loss | Dog ear | Yes | Excellent | Satisfied | no | no | 2 |
P11 | 42 | 27 | I | Excision + liposuction | Yes | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 2 |
P12 | 35 | 29 | I | Excision + liposuction | Yes | Post-weight loss | None | No | Excellent | Very satisfied | yes | no | 2 |
P13 | 28 | 31 | II | Excision + liposuction | Yes | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 2 |
P14 | 39 | 26 | I | Excision only | No | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 3 |
P15 | 52 | 27 | I | Excision + liposuction | Yes | Age | None | No | Excellent | Very satisfied | no | no | 2 |
P16 | 36 | 28.5 | I | Excision + liposuction | Yes | Post-weight loss | Wound dehiscence | No | Excellent | Very satisfied | no | no | 2 |
P17 | 43 | 29 | I | Excision + liposuction | Yes | Post-weight loss | None | No | Good | Very satisfied | no | no | 2 |
P18 | 45 | 30.5 | II | Excision + liposuction | Yes | Post-weight loss | None | No | Good | Very satisfied | no | no | 2 |
P19 | 46 | 32 | II | Excision + liposuction | Yes | Age | None | No | Excellent | Very satisfied | no | no | 2 |
P20 | 37 | 28 | I | Excision + liposuction | Yes | Post-weight loss | None | No | Good | Very satisfied | yes | no | 1 |
P21 | 36 | 26.5 | I | Excision + liposuction | Yes | Post-weight loss | Scar migration | No | Excellent | Very satisfied | no | no | 2 |
P22 | 45 | 28 | I | Excision + liposuction | Yes | Post-weight loss | Scar migration | No | Good | Satisfied | no | no | 2 |
P23 | 50 | 31 | II | Excision + liposuction | Yes | Age | None | No | Excellent | Very satisfied | no | no | 2 |
P24 | 61 | 26 | I | Excision only | No | Age | Wound dehiscence | No | Excellent | Very satisfied | no | no | 2 |
P25 | 36 | 25 | I | Excision only | No | Post-weight loss | None | No | Good | Very satisfied | yes | no | 1 |
P26 | 55 | 25 | I | Excision only | No | Age | None | No | Excellent | Very satisfied | no | no | 1 |
P27 | 47 | 27.5 | I | Excision + liposuction | Yes | Post-weight loss | Hypertrophic scar | No | Excellent | Very satisfied | yes | no | 2 |
P28 | 33 | 24 | I | Excision only | No | Post-weight loss | None | No | Excellent | Very satisfied | no | yes | 2 |
P29 | 45 | 29 | I | Excision + liposuction | Yes | Post-weight loss | Wound dehiscence | No | Excellent | Very satisfied | no | no | 2 |
P30 | 39 | 28 | I | Excision + liposuction | Yes | Post-weight loss | Dog ear | Yes | Good | Satisfied | no | no | 2 |
P31 | 42 | 24.5 | I | Excision only | No | Post-weight loss | None | No | Good | Very satisfied | no | no | 2 |
P32 | 50 | 27 | I | Excision + liposuction | Yes | Age | None | No | Excellent | Very satisfied | no | no | 2 |
P33 | 46 | 26 | I | Excision + liposuction | Yes | Post-weight loss | Dog ear | Yes | Excellent | Very satisfied | yes | no | 2 |
P34 | 41 | 29.5 | II | Excision + liposuction | Yes | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 2 |
P35 | 36 | 23 | I | Excision only | No | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 1 |
P36 | 29 | 28 | I | Excision + liposuction | Yes | Post-weight loss | None | No | Good | Very satisfied | no | no | 2 |
P37 | 31 | 27 | I | Excision + liposuction | Yes | Post-weight loss | Wound dehiscence | No | Good | Very satisfied | yes | no | 2 |
P38 | 43 | 31 | II | Excision + liposuction | Yes | Post-weight loss | None | No | Good | Very satisfied | no | no | 2 |
P39 | 35 | 26 | I | Excision + liposuction | Yes | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 1 |
P40 | 41 | 31 | II | Excision + liposuction | Yes | Post-weight loss | Scar migration | No | Good | Very satisfied | no | no | 2 |
P41 | 49 | 27 | I | Excision + liposuction | Yes | Age | Wound dehiscence | No | Good | Very satisfied | yes | yes | 2 |
P42 | 37 | 28 | I | Excision + liposuction | Yes | Post-weight loss | None | No | Excellent | Very satisfied | no | no | 2 |
P43 | 51 | 25 | I | Excision only | No | Post-weight loss | None | No | Good | Very satisfied | no | no | 1 |
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Ziani, F.; Filigheddu, E.; Arrica, G.; De Riso, S.; Marcaccini, G.; Cuomo, R.; Trignano, C.; Rubino, C.; Trignano, E. Medial Thigh Lift with Tumescent Local Anesthesia: Advancing Outpatient Body Contouring. J. Clin. Med. 2025, 14, 5630. https://doi.org/10.3390/jcm14165630
Ziani F, Filigheddu E, Arrica G, De Riso S, Marcaccini G, Cuomo R, Trignano C, Rubino C, Trignano E. Medial Thigh Lift with Tumescent Local Anesthesia: Advancing Outpatient Body Contouring. Journal of Clinical Medicine. 2025; 14(16):5630. https://doi.org/10.3390/jcm14165630
Chicago/Turabian StyleZiani, Federico, Edoardo Filigheddu, Giovanni Arrica, Sofia De Riso, Gianluca Marcaccini, Roberto Cuomo, Claudia Trignano, Corrado Rubino, and Emilio Trignano. 2025. "Medial Thigh Lift with Tumescent Local Anesthesia: Advancing Outpatient Body Contouring" Journal of Clinical Medicine 14, no. 16: 5630. https://doi.org/10.3390/jcm14165630
APA StyleZiani, F., Filigheddu, E., Arrica, G., De Riso, S., Marcaccini, G., Cuomo, R., Trignano, C., Rubino, C., & Trignano, E. (2025). Medial Thigh Lift with Tumescent Local Anesthesia: Advancing Outpatient Body Contouring. Journal of Clinical Medicine, 14(16), 5630. https://doi.org/10.3390/jcm14165630