Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study
Abstract
1. Introduction
2. Patients and Methods
2.1. Patients
2.2. Surgical Procedure
2.3. Preoperative and Postoperative Examinations
2.4. Statistical Analysis
3. Results
3.1. Change in Clinical Parameters after Ex-PRESS Implantation
3.2. Comparison of CECD in Ex-PRESS-Implanted Eyes and Contralateral Eyes
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Characteristics | Number |
---|---|
Sex (M/F) | 36/12 |
Age at surgery (years) | 51.02 ± 17.96 |
Diagnosis, Number of eyes (rate) | |
Primary open-angle glaucoma | 42 (87.5%) |
Secondary glaucoma | 6 (12.5%) |
pigmentary glaucoma | 1 (2.1%) |
angle-recession glaucoma | 5 (10.4%) |
Preoperative IOP (mm Hg) | 27.42 ± 9.73 |
Number of preoperative IOP-lowering medications | 2.79 ± 1.10 |
Preoperative corneal endothelial cell density (cells/mm2) | 2427.69 ± 473.82 |
The follow up period (years) | 2.43 ± 0.63 |
Complete success eyes (rate) * | 35 (73.1%) |
Qualified success eyes (rate) * | 44 (91.7%) |
Clinical Parameters | Baseline | 6 Months | 12 Months | Final Follow up (>2 Years) |
---|---|---|---|---|
N (eyes) | 48 | 42 | 32 | 48 |
LogMAR BCVA | 0.45 ± 0.45 | 0.44 ± 0.39 | 0.42 ± 0.41 | 0.39 ± 0.36 |
p | 0.564 | 0.577 | 0.169 | |
IOP (mm Hg) | 27.42 ± 9.73 | 14.31 ± 3.43 | 14.16 ± 2.98 | 13.49 ± 2.62 |
p | 0.000 | 0.000 | 0.000 | |
medications | 2.79 ± 1.10 | 0.67 ± 1.00 | 0.71 ± 0.92 | 0.47 ± 0.69 |
p | 0.000 | 0.000 | 0.000 |
Follow-Up Period | N | Operated Eyes | p a | Contralateral Eyes | p b | p c |
---|---|---|---|---|---|---|
Baseline | 48 | 2427.69 ± 473.82 | 2536.16 ± 435.36 | 0.879 | ||
6 months | 31 | 2407.70 ± 593.91 | 0.384 | 2475.94 ± 292.94 | 0.978 | 0.523 |
reduction (%) | 1.6 ± 12.6 | 1.0 ± 9.0 | 0.631 | |||
12 months | 42 | 2364.28 ± 554.44 | 0.255 | 2417.18 ± 381.16 | 0.272 | 0.623 |
reduction (%) | 2.2 ± 8.1 | 1.8 ± 5.0 | 0.572 | |||
Final | 48 | 2316.70 ± 534.77 | 0.017 | 2401.47 ± 410.31 | 0.012 | 0.178 |
reduction (%) | 5.0 ± 12.2 | 3.2 ± 7.8 | 0.130 |
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Ren, X.; Wang, J.; Li, X.; Wu, L. Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study. J. Clin. Med. 2022, 11, 5555. https://doi.org/10.3390/jcm11195555
Ren X, Wang J, Li X, Wu L. Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study. Journal of Clinical Medicine. 2022; 11(19):5555. https://doi.org/10.3390/jcm11195555
Chicago/Turabian StyleRen, Xiaotong, Jie Wang, Xuemin Li, and Lingling Wu. 2022. "Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study" Journal of Clinical Medicine 11, no. 19: 5555. https://doi.org/10.3390/jcm11195555
APA StyleRen, X., Wang, J., Li, X., & Wu, L. (2022). Long-Term Changes in Corneal Endothelial Cell Density after Ex-PRESS Implantation: A Contralateral Eye Study. Journal of Clinical Medicine, 11(19), 5555. https://doi.org/10.3390/jcm11195555