Altered Functional Connectivity and Complexity in Major Depressive Disorder after Musical Stimulation
Abstract
:1. Introduction
2. Materials and Methods
2.1. Participants
- (1)
- Age matching with depression patients.
- (2)
- In good physical and mental health, with no history of mental illness.
- (3)
- A PHQ-9 questionnaire score of less than 4.
- (4)
- Exclusion of individuals with chronic diseases.
- (5)
- Cognitively normal, no history of major depression, schizophrenia, bipolar disorder, or drug abuse, and no medication that may affect cognition and walking.
2.2. EEG Data Acquisition and Preprocessing
2.3. Experimental Paradigm
2.4. Data Analysis
2.4.1. Phase Locking Value
2.4.2. Network Characteristics
3. Results
3.1. Network Analysis
3.2. Network Properties
3.3. Classification
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
References
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MDD (n = 8) | HC (n = 8) | p | |||
---|---|---|---|---|---|
Average | SD | Average | SD | ||
age | 30.85 | 7.5 | 27.65 | 8.6 | 0.89 |
gender | 6 male/2 female | 8 male | |||
PHQ-9 | 15.42 | 5.32 | 2.44 | 0.92 | 0.00 |
GAD-7 | 11.62 | 6.50 | 2.19 | 3.74 | 0.00 |
Classifier | Accuracy | Precision | Recall |
---|---|---|---|
KNN | 81.25% | 75% | 68.75% |
SVM | 93.75% | 87.5% | 93.75% |
DT | 68.75% | 62.5% | 62.5% |
RF | 75% | 68.75% | 75% |
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Qiu, P.; Dai, J.; Wang, T.; Li, H.; Ma, C.; Xi, X. Altered Functional Connectivity and Complexity in Major Depressive Disorder after Musical Stimulation. Brain Sci. 2022, 12, 1680. https://doi.org/10.3390/brainsci12121680
Qiu P, Dai J, Wang T, Li H, Ma C, Xi X. Altered Functional Connectivity and Complexity in Major Depressive Disorder after Musical Stimulation. Brain Sciences. 2022; 12(12):1680. https://doi.org/10.3390/brainsci12121680
Chicago/Turabian StyleQiu, Pintao, Jinxiao Dai, Ting Wang, Hangcheng Li, Cunbin Ma, and Xugang Xi. 2022. "Altered Functional Connectivity and Complexity in Major Depressive Disorder after Musical Stimulation" Brain Sciences 12, no. 12: 1680. https://doi.org/10.3390/brainsci12121680