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Open AccessArticle

Analysis of Protein–Receptor Interactions on an Example of Leptin–Leptin Receptor Interaction Using the Resonant Recognition Model

1
AMALNA Consulting, Black Rock, Melbourne VIC 3193, Australia
2
College of Science, Engineering and Health, RMIT University, Melbourne VIC 3000, Australia
3
Tithon Biotech Inc., San Diego, CA 92127, USA
*
Author to whom correspondence should be addressed.
Appl. Sci. 2019, 9(23), 5169; https://doi.org/10.3390/app9235169
Received: 8 September 2019 / Revised: 25 November 2019 / Accepted: 27 November 2019 / Published: 28 November 2019
(This article belongs to the Special Issue Electromagnetic Radiation in Biology and Health)
Obesity is a medical condition in which excess body fat may have a negative effect on health and lifestyle, and it is becoming an increasing problem within modern society. Leptin is the key protein that regulates body energy balance by inhibiting hunger, and it could potentially be used in treatment of obesity and overweight. Here, we applied our own Resonant Recognition Model, which is capable of analyzing the selectivity of any protein–receptor interaction on an example of leptin–leptin receptor. We have identified a specific characteristic parameter for leptin activity through the leptin receptor, and this parameter could be used in development of new treatments for obesity. View Full-Text
Keywords: obesity; protein–receptor interaction; leptin; electromagnetic radiation; resonant recognition model obesity; protein–receptor interaction; leptin; electromagnetic radiation; resonant recognition model
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Cosic, I.; Paspaliaris, V.; Cosic, D. Analysis of Protein–Receptor Interactions on an Example of Leptin–Leptin Receptor Interaction Using the Resonant Recognition Model. Appl. Sci. 2019, 9, 5169.

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