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Open AccessArticle

An Efficient Automatic Midsagittal Plane Extraction in Brain MRI

1
Department of Mechatronics Engineering, Hanyang University, Ansan 15588, Korea
2
School of Electrical Engineering, Hanyang University, Ansan 15588, Korea
*
Author to whom correspondence should be addressed.
Appl. Sci. 2018, 8(11), 2203; https://doi.org/10.3390/app8112203
Received: 16 October 2018 / Revised: 2 November 2018 / Accepted: 6 November 2018 / Published: 9 November 2018
(This article belongs to the Special Issue Intelligent Imaging and Analysis)
In this paper, a fully automatic and computationally efficient midsagittal plane (MSP) extraction technique in brain magnetic resonance images (MRIs) has been proposed. Automatic detection of MSP in neuroimages can significantly aid in registration of medical images, asymmetric analysis, and alignment or tilt correction (recenter and reorientation) in brain MRIs. The parameters of MSP are estimated in two steps. In the first step, symmetric features and principal component analysis (PCA)-based technique is used to vertically align the bilateral symmetric axis of the brain. In the second step, PCA is used to achieve a set of parallel lines (principal axes) from the selected two-dimensional (2-D) elliptical slices of brain MRIs, followed by a plane fitting using orthogonal regression. The developed algorithm has been tested on 157 real T1-weighted brain MRI datasets including 14 cases from the patients with brain tumors. The presented algorithm is compared with a state-of-the-art approach based on bilateral symmetry maximization. Experimental results revealed that the proposed algorithm is fast (<1.04 s per MRI volume) and exhibits superior performance in terms of accuracy and precision (a mean z-distance of 0.336 voxels and a mean angle difference of 0.06). View Full-Text
Keywords: medical image registration; image alignment in medical images; misalignment correction in MRI; midsagittal plane extraction; symmetry detection; PCA medical image registration; image alignment in medical images; misalignment correction in MRI; midsagittal plane extraction; symmetry detection; PCA
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Rehman, H.Z.U.; Lee, S. An Efficient Automatic Midsagittal Plane Extraction in Brain MRI. Appl. Sci. 2018, 8, 2203.

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