Effect of Acute Consumption of Crackers Enriched with Grape Seed Flour or Barley Flour with Added β-Glucan on Biomarkers of Postprandial Glycemia, Lipidemia, and Oxidative Stress: A Crossover Study

Chatziharalambous, Despina; Papagianni, Olga; Potsaki, Panagiota; Almpounioti, Kalliopi; Koutelidakis, Antonios E.

doi:10.3390/app14114591

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Effect of Acute Consumption of Crackers Enriched with Grape Seed Flour or Barley Flour with Added β-Glucan on Biomarkers of Postprandial Glycemia, Lipidemia, and Oxidative Stress: A Crossover Study

by

Despina Chatziharalambous

,

Olga Papagianni

,

Panagiota Potsaki

,

Kalliopi Almpounioti

and

Antonios E. Koutelidakis

^*

Unit of Human Nutrition, Laboratory of Nutrition and Public Health, Department of Food Science and Nutrition, University of the Aegean, Leoforos Dimokratias 66, Myrina, 81400 Lemnos, Greece

^*

Author to whom correspondence should be addressed.

Appl. Sci. 2024, 14(11), 4591; https://doi.org/10.3390/app14114591

Submission received: 17 April 2024 / Revised: 22 May 2024 / Accepted: 23 May 2024 / Published: 27 May 2024

(This article belongs to the Special Issue Functional Foods and Natural Products: Bioactive Compounds and Beneficial Effects on Health – Volume II)

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Abstract

Background: Grape seed polyphenol bioactivity is linked to reduced risk of metabolic syndrome, type 2 diabetes, obesity, and coronary heart disease development. Furthermore, regular consumption of β-glucan is associated with decreased lipidemic and glycemic profiles. The aim was to investigate the acute effect of crackers enriched with either 10% grape seed flour or 40% barley flour with added β-glucan along with a high-fat and high-carbohydrate meal on biomarkers of postprandial glycemia, lipidemia, and oxidative stress. Methods: In a randomized, three-arm crossover design study, 12 healthy subjects were assigned to consume breakfast consisting of bread, butter, and 250 mL water along with crackers containing either (a) wheat flour, (b) 10% grape seed flour, or (c) 40% barley flour enriched with β-glucan. Blood samples were drawn immediately before and 30, 90, and 180 min after the meal. Total antioxidant capacity was measured in plasma with the FRAP method. Total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, glucose, and uric acid were measured in serum. Results: Tested markers did not differ between the intervention groups at baseline, 30, 90, and 180 min (p ≥ 0.05) post-prandially. Conclusions: Enriched cracker consumption did not significantly affect the selected markers at the postprandial state, although better serum glucose and lipid levels, similar to baseline values, were maintained.

Keywords: grape seed flour; barley flour; crackers; glycemia; oxidative stress; lipidemia

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MDPI and ACS Style

Chatziharalambous, D.; Papagianni, O.; Potsaki, P.; Almpounioti, K.; Koutelidakis, A.E. Effect of Acute Consumption of Crackers Enriched with Grape Seed Flour or Barley Flour with Added β-Glucan on Biomarkers of Postprandial Glycemia, Lipidemia, and Oxidative Stress: A Crossover Study. Appl. Sci. 2024, 14, 4591. https://doi.org/10.3390/app14114591

AMA Style

Chatziharalambous D, Papagianni O, Potsaki P, Almpounioti K, Koutelidakis AE. Effect of Acute Consumption of Crackers Enriched with Grape Seed Flour or Barley Flour with Added β-Glucan on Biomarkers of Postprandial Glycemia, Lipidemia, and Oxidative Stress: A Crossover Study. Applied Sciences. 2024; 14(11):4591. https://doi.org/10.3390/app14114591

Chicago/Turabian Style

Chatziharalambous, Despina, Olga Papagianni, Panagiota Potsaki, Kalliopi Almpounioti, and Antonios E. Koutelidakis. 2024. "Effect of Acute Consumption of Crackers Enriched with Grape Seed Flour or Barley Flour with Added β-Glucan on Biomarkers of Postprandial Glycemia, Lipidemia, and Oxidative Stress: A Crossover Study" Applied Sciences 14, no. 11: 4591. https://doi.org/10.3390/app14114591

APA Style

Chatziharalambous, D., Papagianni, O., Potsaki, P., Almpounioti, K., & Koutelidakis, A. E. (2024). Effect of Acute Consumption of Crackers Enriched with Grape Seed Flour or Barley Flour with Added β-Glucan on Biomarkers of Postprandial Glycemia, Lipidemia, and Oxidative Stress: A Crossover Study. Applied Sciences, 14(11), 4591. https://doi.org/10.3390/app14114591

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Effect of Acute Consumption of Crackers Enriched with Grape Seed Flour or Barley Flour with Added β-Glucan on Biomarkers of Postprandial Glycemia, Lipidemia, and Oxidative Stress: A Crossover Study

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