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Medical Sciences, Volume 8, Issue 2

June 2020 - 6 articles

Cover Story: Cardiac remodeling requires the ability of cardiomyocytes to adapt to an alterations in three-dimensional structure of the heart. This complex scenario can be studied ex vivo by challenging isolated ventricular cardiomyocytes to adapt to a two-dimensional cell culture dish. Using this approach, it was shown that growth factors can induce the expression of proteasome subunit low molecular weight protein (LMP)-2 . Obviously, this accelerates proteasomal degradation of sarcomere proteins, allowing the cells to rearrange their sarcomeres as required for adaptation to altered environments. Without this induction, cells are unable to de-arrange their existing sarcomeres and subsequently unable to rebuild new sarcomeres as required for successful survival.

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Article

6 Citations

10,214 Views

9 Pages

Osteopathic Manipulative Treatment in Neonatal Intensive Care Units

Luca Cicchitti,
Alessandra Di Lelio,
Gina Barlafante,
Vincenzo Cozzolino,
Susanna Di Valerio,
Paola Fusilli,
Giuseppe Lucisano,
Cinzia Renzetti,
Marco Verzella and
Maria Chiara Rossi

Med. Sci.2020, 8(2), 24;https://doi.org/10.3390/medsci8020024

24 June 2020

The aim of this study was to assess the impact of osteopathic manipulative treatment (OMT) on newborn babies admitted at a neonatal intensive care unit (NICU). This was an observational, longitudinal, retrospective study. All consecutive admitted bab...

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Article

23 Citations

6,387 Views

10 Pages

An Exploratory Study of Quality of Life and Its Relationship with Academic Performance among Students in Medical and other Health Professions

Vijay Kumar Chattu,
Pradeep Kumar Sahu,
Neela Seedial,
Gerlisa Seecharan,
Amanda Seepersad,
Melina Seunarine,
Shivanna Sieunarine,
Kahamaron Seymour,
Samantha Simboo and
Arissa Singh

Med. Sci.2020, 8(2), 23;https://doi.org/10.3390/medsci8020023

9 June 2020

Quality of life (QOL) is a broader concept which represents experiences, states, appraisals, behaviors, capacities and emotional reactions to circumstances. The study aimed to evaluate the differences in various domains of QOL among the students of f...

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Article

8 Citations

4,658 Views

9 Pages

Serum Chloride Levels at Hospital Discharge and One-Year Mortality among Hospitalized Patients

Tananchai Petnak,
Charat Thongprayoon,
Wisit Cheungpasitporn,
Tarun Bathini,
Saraschandra Vallabhajosyula,
Api Chewcharat and
Kianoush Kashani

Med. Sci.2020, 8(2), 22;https://doi.org/10.3390/medsci8020022

19 May 2020

This study aimed to assess the one-year mortality risk based on discharge serum chloride among the hospital survivors. We analyzed a cohort of adult hospital survivors at a tertiary referral hospital from 2011 through 2013. We categorized discharge s...

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Article

5 Citations

3,332 Views

15 Pages

Induction of Proteasome Subunit Low Molecular Weight Protein (LMP)-2 Is Required to Induce Active Remodeling in Adult Rat Ventricular Cardiomyocytes

Antonia Petersen,
Hanna Sarah Kutsche,
Franziska Nippert,
Rolf Schreckenberg,
Rainer Schulz and
Klaus-Dieter Schlüter

Med. Sci.2020, 8(2), 21;https://doi.org/10.3390/medsci8020021

1 May 2020

Isolated adult rat ventricular cardiomyocytes (ARVC) adapt to the two-dimensional surface of culture dishes once they are isolated from the three-dimensional heart tissue. This process mimics aspects of cardiac adaptation to pressure overload and req...

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Article

40 Citations

6,946 Views

9 Pages

Advances and Challenges in European Paediatric Palliative Care

Lorna K Fraser,
Myra Bluebond-Langner and
Julie Ling

Med. Sci.2020, 8(2), 20;https://doi.org/10.3390/medsci8020020

17 April 2020

Advances in both public health and medical interventions have resulted in a reduction in childhood mortality worldwide over the last few decades; however, children still have life-threatening conditions that require palliative care. Children’s...

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Article

20 Citations

3,828 Views

8 Pages

Atmospheric Pollution and Thyroid Function of Pregnant Women in Athens, Greece: A Pilot Study

Ioannis Ilias,
Ioannis Kakoulidis,
Stefanos Togias,
Stefanos Stergiotis,
Aikaterini Michou,
Anastasia Lekkou,
Vasiliki Mastrodimou,
Athina Pappa,
Evangelia Venaki and
Eftychia Koukkou

Med. Sci.2020, 8(2), 19;https://doi.org/10.3390/medsci8020019

4 April 2020

Exposure to air pollution and, in particular, to nitrogen dioxide (NO2) or particulate pollutants less than 2.5 μm (PM2.5) or 10 μm (PM10) in diameter has been linked to thyroid (dys)function in pregnant women. We hypothesized that there may be...

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