Clinical Escherichia coli: From Biofilm Formation to New Antibiofilm Strategies
1
ISGlobal, Hospital Clínic, Universitat de Barcelona, 08036 Barcelona, Spain
2
CIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain
*
Author to whom correspondence should be addressed.
Academic Editors: Grzegorz Wegrzyn and Ute Römling
Microorganisms 2022, 10(6), 1103; https://doi.org/10.3390/microorganisms10061103
Received: 11 May 2022
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Revised: 23 May 2022
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Accepted: 24 May 2022
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Published: 26 May 2022
(This article belongs to the Special Issue Feature Papers in Microbial Biofilm Formation)
Escherichia coli is one of the species most frequently involved in biofilm-related diseases, being especially important in urinary tract infections, causing relapses or chronic infections. Compared to their planktonic analogues, biofilms confer to the bacteria the capacity to be up to 1000-fold more resistant to antibiotics and to evade the action of the host’s immune system. For this reason, biofilm-related infections are very difficult to treat. To develop new strategies against biofilms, it is important to know the mechanisms involved in their formation. In this review, the different steps of biofilm formation in E. coli, the mechanisms of tolerance to antimicrobials and new compounds and strategies to combat biofilms are discussed.
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MDPI and ACS Style
Ballén, V.; Cepas, V.; Ratia, C.; Gabasa, Y.; Soto, S.M. Clinical Escherichia coli: From Biofilm Formation to New Antibiofilm Strategies. Microorganisms 2022, 10, 1103. https://doi.org/10.3390/microorganisms10061103
AMA Style
Ballén V, Cepas V, Ratia C, Gabasa Y, Soto SM. Clinical Escherichia coli: From Biofilm Formation to New Antibiofilm Strategies. Microorganisms. 2022; 10(6):1103. https://doi.org/10.3390/microorganisms10061103
Chicago/Turabian StyleBallén, Victoria, Virginio Cepas, Carlos Ratia, Yaiza Gabasa, and Sara M. Soto. 2022. "Clinical Escherichia coli: From Biofilm Formation to New Antibiofilm Strategies" Microorganisms 10, no. 6: 1103. https://doi.org/10.3390/microorganisms10061103
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