Seroprevalence of Hepatitis E Virus in Forestry Workers from Trentino-Alto Adige Region (Northern Italy)
Abstract
:1. Introduction
2. Methods
2.1. Study Groups
2.2. Seroprevalence of IgG Anti-HEV
2.3. Detection of Anti-HEV IgM Antibodies by Western Blotting
2.4. Viral Extraction and Real-Time RT-PCR
2.5. Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Acknowledgments
Conflicts of Interest
References
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Median Age | Group | ELISA Anti-IgG Positive/Total | Prevalence (%) | 95%CI | p |
---|---|---|---|---|---|
≤48 | Forestry workers | 6/71 | 8.5 | 3.2–17.5 | 0.53 |
Control group | 6/45 | 13.3 | 5.1–26.8 | ||
Total | 12/116 | 10.3 | 5.5–17.4 | ||
≥49 | Forestry workers | 15/79 | 19.0 | 11.0–29.4 | 0.04 |
Control group | 2/40 | 5.0 | 0.6–16.9 | ||
Total | 17/119 | 14.3 | 8.6–21.9 | ||
Total | Forestry workers | 21/150 | 14.0 | 8.9–20.6 | 0.30 |
Control group | 8/85 | 9.4 | 4.2–17.7 | ||
Total | 29/235 | 12.3 | 8.4–17.2 |
Risk Factor | Odds Ratio | 95%CI | p |
---|---|---|---|
Group | |||
Forestry workers | 1.67 | 0.50–5.53 | 0.40 |
Control group | referent | - | - |
Age | |||
≥49 | 2.92 | 0.55–15.40 | 0.21 |
≤48 | referent | - | - |
Interaction group × age | 7.42 | 1.06–51.81 | 0.04 |
Constant | 6.50 | 0 |
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Monini, M.; Ostanello, F.; Dominicis, A.; Tagliapietra, V.; Vaccari, G.; Rizzoli, A.; Trombetta, C.M.; Montomoli, E.; Di Bartolo, I. Seroprevalence of Hepatitis E Virus in Forestry Workers from Trentino-Alto Adige Region (Northern Italy). Pathogens 2020, 9, 568. https://doi.org/10.3390/pathogens9070568
Monini M, Ostanello F, Dominicis A, Tagliapietra V, Vaccari G, Rizzoli A, Trombetta CM, Montomoli E, Di Bartolo I. Seroprevalence of Hepatitis E Virus in Forestry Workers from Trentino-Alto Adige Region (Northern Italy). Pathogens. 2020; 9(7):568. https://doi.org/10.3390/pathogens9070568
Chicago/Turabian StyleMonini, Marina, Fabio Ostanello, Alessandra Dominicis, Valentina Tagliapietra, Gabriele Vaccari, Annapaola Rizzoli, Claudia M. Trombetta, Emanuele Montomoli, and Ilaria Di Bartolo. 2020. "Seroprevalence of Hepatitis E Virus in Forestry Workers from Trentino-Alto Adige Region (Northern Italy)" Pathogens 9, no. 7: 568. https://doi.org/10.3390/pathogens9070568