Next Article in Journal
Patient and Clinician Preferences for Genetic and Genomic Testing in Non-Small Cell Lung Cancer: A Discrete Choice Experiment
Next Article in Special Issue
Diagnostic Performance of the Rapid Antigen Test as a Screening Tool for SARS-CoV-2 Infection in the Emergency Department
Previous Article in Journal
Antibiotic Prescription and In-Hospital Mortality in COVID-19: A Prospective Multicentre Cohort Study
Previous Article in Special Issue
The Genomic Profile Associated with Risk of Severe Forms of COVID-19 in Amazonian Native American Populations
 
 
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

Predictive Value of SOFA and qSOFA for In-Hospital Mortality in COVID-19 Patients: A Single-Center Study in Romania

1
Department of Obstetrics and Gynecology, “Victor Babes” University of Medicine and Pharmacy Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania
2
Department of Internal Medicine I, “Victor Babes” University of Medicine and Pharmacy Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania
3
Department of Anatomy and Embryology, “Victor Babes” University of Medicine and Pharmacy Timisoara, 2 Eftimie Murgu Square, 300041 Timisoara, Romania
4
Department of Obstetrics and Gynecology, Municipal Emergency Clinical Hospital Timisoara, 1-3 Alexandru Odobescu Street, 300202 Timisoara, Romania
*
Author to whom correspondence should be addressed.
J. Pers. Med. 2022, 12(6), 878; https://doi.org/10.3390/jpm12060878
Submission received: 5 May 2022 / Revised: 24 May 2022 / Accepted: 25 May 2022 / Published: 26 May 2022
(This article belongs to the Special Issue Recent Advances on Coronavirus Disease 2019 (COVID-19))

Abstract

Two years after the outbreak of the COVID-19 pandemic, the disease continues to claim victims worldwide. Assessing the disease’s severity on admission may be useful in reducing mortality among patients with COVID-19. The present study was designed to assess the prognostic value of SOFA and qSOFA scoring systems for in-hospital mortality among patients with COVID-19. The study included 133 patients with COVID-19 proven by reverse transcriptase polymerase chain reaction (RT-PCR) admitted to the Municipal Emergency Clinical Hospital of Timisoara, Romania between 1 October 2020 and 15 March 2021. Data on clinical features and laboratory findings on admission were collected from electronic medical records and used to compute SOFA and qSOFA. Mean SOFA and qSOFA values were higher in the non-survivor group compared to survivors (3.5 vs. 1 for SOFA and 2 vs. 1 for qSOFA, respectively). Receiver operating characteristic (ROC) and area under the curve (AUC) analyses were performed to determine the discrimination accuracy, both risk scores being excellent predictors of in-hospital mortality, with ROC–AUC values of 0.800 for SOFA and 0.794 for qSOFA. The regression analysis showed that for every one-point increase in SOFA score, mortality risk increased by 1.82 and for every one-point increase in qSOFA score, mortality risk increased by 5.23. In addition, patients with SOFA and qSOFA above the cut-off values have an increased risk of mortality with ORs of 7.46 and 11.3, respectively. In conclusion, SOFA and qSOFA are excellent predictors of in-hospital mortality among COVID-19 patients. These scores determined at admission could help physicians identify those patients at high risk of severe COVID-19.
Keywords: SOFA; qSOFA; COVID-19; prediction SOFA; qSOFA; COVID-19; prediction

Share and Cite

MDPI and ACS Style

Citu, C.; Citu, I.M.; Motoc, A.; Forga, M.; Gorun, O.M.; Gorun, F. Predictive Value of SOFA and qSOFA for In-Hospital Mortality in COVID-19 Patients: A Single-Center Study in Romania. J. Pers. Med. 2022, 12, 878. https://doi.org/10.3390/jpm12060878

AMA Style

Citu C, Citu IM, Motoc A, Forga M, Gorun OM, Gorun F. Predictive Value of SOFA and qSOFA for In-Hospital Mortality in COVID-19 Patients: A Single-Center Study in Romania. Journal of Personalized Medicine. 2022; 12(6):878. https://doi.org/10.3390/jpm12060878

Chicago/Turabian Style

Citu, Cosmin, Ioana Mihaela Citu, Andrei Motoc, Marius Forga, Oana Maria Gorun, and Florin Gorun. 2022. "Predictive Value of SOFA and qSOFA for In-Hospital Mortality in COVID-19 Patients: A Single-Center Study in Romania" Journal of Personalized Medicine 12, no. 6: 878. https://doi.org/10.3390/jpm12060878

APA Style

Citu, C., Citu, I. M., Motoc, A., Forga, M., Gorun, O. M., & Gorun, F. (2022). Predictive Value of SOFA and qSOFA for In-Hospital Mortality in COVID-19 Patients: A Single-Center Study in Romania. Journal of Personalized Medicine, 12(6), 878. https://doi.org/10.3390/jpm12060878

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop