Comprehensive Assessment of Eyes in Kidney Transplant Recipients after Recovering from COVID-19
Abstract
:1. Introduction
2. Materials and Methods
2.1. Design and Participants
2.2. Ophthalmologic Procedures
2.3. Data Collections
2.4. Statistical Analysis
3. Results
4. Discussion
5. Conclusions
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
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Parameter | Study Group (n = 38) | Control Group (n = 18) | p |
---|---|---|---|
Sex | 18 m (47.3%) | 10 m (55.5%) | 0.74 |
Age | 52.5 (45–55) | 42 (36–49) | 0.003 |
RRT (months) | 234 (221–252) | 229.5 (215.5–259.5) | 0.89 |
KTx vintage (months) | 58 (20–138) | 66 (19–146) | 0.84 |
Charlson comorbidity index (CCI) | 3 (2–3) | 2 (2–2) | 0.35 |
Arterial hypertension | 37 | 16 | 0.75 |
Number of hypotensive drugs | 2 | 1.5 | 0.97 |
Stroke | 1 | 0 | 0.95 |
Coronary artery disease | 3 | 1 | 0.67 |
Peripheral artery occlusive disease | 0 | 0 | 0.59 |
Statin therapy | 9 | 7 | 0.22 |
RAAS therapy | 9 | 5 | 0.72 |
ASA | 7 | 6 | 0.18 |
LMWH | 1 | 0 | 0.45 |
NOAC | 1 | 0 | 0.45 |
Parameter | Study Group (n = 38) | Control Group (n = 18) | p |
---|---|---|---|
Creatinine (mg/dL) | 1.34 (0.97–1.67) | 1.39 (0.99–1.79) | 0.33 |
eGFR (ml/min/1.73 m2) CKD-EPI | 52.5 (44–68) | 71 (45–76) | 0.62 |
CRP (mg/L) | 1.73 (0.86–2.53) | 1.04 (0.48–1.82) | 0.43 |
D-dimer (ng/mL) | 394 (243–783) | 509 (348–874) | 0.71 |
Fibrinogen (g/L) | 3.02 (2.8–3.49) | 2.98 (2.54–3.35) | 0.73 |
Hemoglobin (g/dL) | 13.25 (12.5–14.8) | 14.06 (12.8–15.3) | 0.11 |
Hematocrit (%) | 40.35 (37.9–43.6) | 43.5 (39.8–45.9) | 0.49 |
Platelets (109/L) | 219.5 (199–274) | 233 (180–276) | 0.37 |
WBC (109/L) | 8.0 (6.93–9.37) | 8.8 (16.64–10.23) | 0.54 |
Lymphocytes (109/L) | 2.3 (1.53–2.62) | 1.91 (1.27–2.41) | 0.48 |
Parameter | Study Group (n = 76) | Control Group (n = 36) | p |
---|---|---|---|
DCP central (%) | 16.31 (6.37–29.58) | 20.31 (9.89–29.35) | 0.015 * |
DCP superior (%) | 48.28 (33.87–54.74) | 49.19 (43.16–52.21) | 0.08 |
DCP inferior (%) | 47.05 (48.06–35.38) | 48.2 (39.91–53.53) | 0.49 |
DCP nasal (%) | 45.86 (47.04–32.6) | 47.92 (40.15–51.14) | 0.06 |
DCP temporal (%) | 45.78 (46.04–31.53) | 47.73 (42.27–51.22) | 0.07 |
SCP central (%) | 21.34 (13.39–30.61) | 21.45 (13.89–30.4) | 0.87 |
SCP superior (%) | 46.70 (35.03–51.3) | 48.08 (36.88–51.22) | 0.57 |
SCP inferior (%) | 46.31 (35.67–53.28) | 47.4 (36.9–49.79) | 0.79 |
SCP nasal (%) | 45.84 (31.22–50.98) | 47.08 (32.64–52.4) | 0.38 |
SCP temporal (%) | 47.69 (34.81–52.66) | 48.25 (36.73–55.1) | 0.48 |
Parameter | Study Group (n = 76) | Control Group (n = 36) | p |
---|---|---|---|
FAZ superficial (µm2) | 285.50 (114–602) | 275 (60–510) | 0.51 |
FAZ deep (µm2) | 402 (140–770) | 397.5 (185–660) | 0.35 |
CRT (µm) | 234 (182–285) | 229.5 (175–278) | 0.59 |
RNFL (µm) | 100 (64–128) | 99.5 (41–120) | 0.47 |
GCC (µm) | 101.5 (63–124) | 103.5 (70–135) | 0.33 |
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Ślizień, M.; Sulecka, P.; Tylicki, L.; Janicka, Z.; Konopa, J.; Ślizień, Z.; Dębska-Ślizień, A.; Michalska-Małecka, K.; Biedunkiewicz, B. Comprehensive Assessment of Eyes in Kidney Transplant Recipients after Recovering from COVID-19. Life 2023, 13, 2003. https://doi.org/10.3390/life13102003
Ślizień M, Sulecka P, Tylicki L, Janicka Z, Konopa J, Ślizień Z, Dębska-Ślizień A, Michalska-Małecka K, Biedunkiewicz B. Comprehensive Assessment of Eyes in Kidney Transplant Recipients after Recovering from COVID-19. Life. 2023; 13(10):2003. https://doi.org/10.3390/life13102003
Chicago/Turabian StyleŚlizień, Mateusz, Paulina Sulecka, Leszek Tylicki, Zofia Janicka, Joanna Konopa, Zuzanna Ślizień, Alicja Dębska-Ślizień, Katarzyna Michalska-Małecka, and Bogdan Biedunkiewicz. 2023. "Comprehensive Assessment of Eyes in Kidney Transplant Recipients after Recovering from COVID-19" Life 13, no. 10: 2003. https://doi.org/10.3390/life13102003