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Article

Endothelial and Vascular Health: A Tale of Honey, H2O2 and Calcium

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DiSIT—Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Viale Teresa Michel 11, 15121 Alessandria, Italy
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DiSIT—Dipartimento di Scienze e Innovazione Tecnologica, University of Piemonte Orientale, Piazza Sant’Eusebio 5, 13100 Vercelli, Italy
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Author to whom correspondence should be addressed.
Academic Editor: Andreas Fischer
Cells 2021, 10(5), 1071; https://doi.org/10.3390/cells10051071
Received: 12 April 2021 / Accepted: 27 April 2021 / Published: 30 April 2021
(This article belongs to the Special Issue Cellular and Molecular Basis of Wound Healing)
Intracellular Ca2+ regulation plays a pivotal role in endothelial biology as well as during endothelial restoration processes. Interest in honey utilization in wound approaches is rising in recent years. In order to evaluate the positive effects of buckwheat honey on endothelial responses, we utilized an immortalized endothelial cell line to evaluate cellular responses upon honey exposure, with particular interest in Ca2+ signaling involvement. The results highlight the positive effects of buckwheat honey on endothelial cells’ responses and the central role played by Ca2+ signaling as an encouraging target for more efficacious clinical treatments. View Full-Text
Keywords: buckwheat honey; endothelial cells; intracellular calcium; hydrogen peroxide; wound healing buckwheat honey; endothelial cells; intracellular calcium; hydrogen peroxide; wound healing
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MDPI and ACS Style

Ranzato, E.; Bonsignore, G.; Patrone, M.; Martinotti, S. Endothelial and Vascular Health: A Tale of Honey, H2O2 and Calcium. Cells 2021, 10, 1071. https://doi.org/10.3390/cells10051071

AMA Style

Ranzato E, Bonsignore G, Patrone M, Martinotti S. Endothelial and Vascular Health: A Tale of Honey, H2O2 and Calcium. Cells. 2021; 10(5):1071. https://doi.org/10.3390/cells10051071

Chicago/Turabian Style

Ranzato, Elia, Gregorio Bonsignore, Mauro Patrone, and Simona Martinotti. 2021. "Endothelial and Vascular Health: A Tale of Honey, H2O2 and Calcium" Cells 10, no. 5: 1071. https://doi.org/10.3390/cells10051071

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