N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor
Abstract
:1. Introduction
2. NDRG2 Functions as a Tumor Suppressor
3. Proapoptotic Function of NDRG2
3.1. Spermatogenesis and NDRG2
3.2. p53-Mediated Apoptosis and NDRG2
3.3. Sensitivity to Anticancer Drugs and NDRG2
3.4. Metabolic Stress and NDRG2
4. Conclusions/Outlook
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Conflicts of Interest
References
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Kim, G.; Lim, S.; Kim, K.D. N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor. Cells 2021, 10, 2649. https://doi.org/10.3390/cells10102649
Kim G, Lim S, Kim KD. N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor. Cells. 2021; 10(10):2649. https://doi.org/10.3390/cells10102649
Chicago/Turabian StyleKim, Gayeon, Seyeon Lim, and Kwang Dong Kim. 2021. "N-myc Downstream-Regulated Gene 2 (NDRG2) Function as a Positive Regulator of Apoptosis: A New Insight into NDRG2 as a Tumor Suppressor" Cells 10, no. 10: 2649. https://doi.org/10.3390/cells10102649