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Open AccessArticle

In vitro Comparative Study of Fibroblastic Behaviour on Polymethacrylate (PMMA) and Lithium Disilicate Polymer Surfaces

1
Department of Oral Surgery, College of Dentistry, Seville University, 41009 Seville, Spain
2
Department of Dental Protheses, College of Dentistry, Complutense University of Madrid, 28040 Madrid, Spain
*
Author to whom correspondence should be addressed.
Polymers 2019, 11(4), 744; https://doi.org/10.3390/polym11040744
Received: 1 March 2019 / Revised: 18 April 2019 / Accepted: 23 April 2019 / Published: 25 April 2019
(This article belongs to the Special Issue Biomedical Polymer Materials)
Polymethyl methacrylate (PMMA) and lithium disilicate are widely used materials in the dental field. PMMA is mainly used for the manufacture of removable prostheses; however, with the incorporation of CAD-CAM technology, new applications have been introduced for this material, including as a provisional implant attachment. Lithium disilicate is considered the gold standard for definitive attachment material. On the other hand, PMMA has begun to be used in clinics as a provisional attachment until the placement of a definitive one occurs. Although there are clinical studies regarding its use, there are few studies on cell reorganization around this type of material. This is why we carried out an in vitro comparative study using discs of both materials in which human gingival fibroblasts (HGFs) were cultured. After processing them, we analyzed various cellular parameters (cell count, cytoskeleton length, core size and coverage area). We analyzed the surface of the discs together with their composition. The results obtained were mostly not statistically significant, which shows that the qualities of PMMA make it a suitable material as an implant attachment. View Full-Text
Keywords: polymethyl methacrylate (PMMA); cytomorphometry; lithium silicate; gingival fibroblast; computer-aided design/computer-aided manufacturing (CAD/CAM); early cell proliferation polymethyl methacrylate (PMMA); cytomorphometry; lithium silicate; gingival fibroblast; computer-aided design/computer-aided manufacturing (CAD/CAM); early cell proliferation
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Herráez-Galindo, C.; Rizo-Gorrita, M.; Luna-Oliva, I.; Serrera-Figallo, M.-Á.; Castillo-Oyagüe, R.; Torres-Lagares, D. In vitro Comparative Study of Fibroblastic Behaviour on Polymethacrylate (PMMA) and Lithium Disilicate Polymer Surfaces. Polymers 2019, 11, 744.

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