Effects of Proton Pump Inhibitor Administration and Intake of a Combination of Yogurt and Galactooligosaccharides on Bone and Mineral Metabolism in Rats
Abstract
:1. Introduction
2. Experimental Section
2.1. Diets
2.2. Animals
2.3. BMD by X-ray CT Analysis
2.4. Dynamic Bone Histomorphometry
2.5. Calcium and Phosphorus Absorption
2.6. Biochemical Analysis
2.7. Statistics
3. Results
3.1. Body Weight and Whole Caecal Weight
3.2. BMD of the Femur and the LV
3.3. Dynamic Bone Histomorphometry
3.4. Biochemical Analysis
3.5. Calcium and Phosphorus Absorption
4. Discussion
5. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Control (AIN-93M) | Yogurt + GOS | |
---|---|---|
Ingredients (g/kg diet) | ||
Corn starch | 447.10 | 333.03 |
α-corn starch | 155.00 | 155.00 |
Casein | 140.00 | 46.67 |
Lyophilized yogurt | 0.00 | 220.50 |
Sucrose | 100.00 | 32.25 |
Soybean oil | 40.00 | 40.00 |
Cellulose powder | 50.00 | 50.00 |
AIN-93M mineral premix without calcium and phosphorus | 35.00 | 35.00 |
Calcium carbonate | 12.41 | 5.54 |
Potassium phosphate | 8.69 | 2.46 |
AIN-93 vitamin premix including choline bitartrate | 10.00 | 10.00 |
l-Cystine | 1.80 | 1.80 |
GOS ingredient | 0.00 | 67.75 |
Calculated value (g/kg diet) | ||
Crude protein | 118.70 | 118.70 |
Calcium | 5.00 | 5.00 |
Phosphorus | 3.00 | 3.00 |
GOS | 0.00 | 50.00 |
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Takasugi, S.; Shioyama, M.; Kitade, M.; Nagata, M.; Yamaji, T. Effects of Proton Pump Inhibitor Administration and Intake of a Combination of Yogurt and Galactooligosaccharides on Bone and Mineral Metabolism in Rats. Nutrients 2016, 8, 653. https://doi.org/10.3390/nu8100653
Takasugi S, Shioyama M, Kitade M, Nagata M, Yamaji T. Effects of Proton Pump Inhibitor Administration and Intake of a Combination of Yogurt and Galactooligosaccharides on Bone and Mineral Metabolism in Rats. Nutrients. 2016; 8(10):653. https://doi.org/10.3390/nu8100653
Chicago/Turabian StyleTakasugi, Satoshi, Miho Shioyama, Masami Kitade, Masashi Nagata, and Taketo Yamaji. 2016. "Effects of Proton Pump Inhibitor Administration and Intake of a Combination of Yogurt and Galactooligosaccharides on Bone and Mineral Metabolism in Rats" Nutrients 8, no. 10: 653. https://doi.org/10.3390/nu8100653