NutriWomen, Novel Evidence-Based Web Platform to Support Women’s Health, Nutrition Decisions and Address Nutrition Misinformation on Social Media: Protocol for a Digital Tool Development
Abstract
1. Introduction
- (1)
- To identify, collect, select, and classify nutrition-related claims, as well as dietary or nutrient recommendations, disseminated on Instagram and targeted to women at their reproductive age or later aging.
- (2)
- To assess the information quality of these claims and/or recommendations disseminated on Instagram using structured checklists of criteria.
- (3)
- To assess the methodological soundness and scientific confidence of the supporting evidence, using the GRADE framework when available.
- (4)
- To develop a web- and social media–based resource that translates research findings into accessible, engaging, and user-friendly formats, aimed at empowering women to make informed, evidence-based decisions to improve their nutrition-related health outcomes.
- (5)
- To assess women’s perceptions of this resource, its usefulness, accessibility, and relevance, through a pilot study involving focus groups.
2. Experimental Design
3. Detailed Procedure
- Headline: States the question of the evaluation or the intervention and outcomes in one sentence.
- Quality of information: Provides the overall information quality grade and a summary of met and unmet quality criteria (see “Stage 2” for further details).
- Quality and certainty of the evidence: Provides the overall score of the methodological quality of the systematic review and a summary of met and unmet quality criteria (see “Stage 3” for further details), whenever there is a SR that evaluates the claim of interest. This section will only be included in the version intended for healthcare providers, while the general public version will feature a simplified visual summary.
- Critical thinking advice: Includes a brief reflection or tip designed to assist the audience in identifying inaccurate claims or recommendations and making informed decisions regarding health and nutrition.
3.1. Participants
3.2. Data Collection and Analysis
4. Expected Results
4.1. Ethical Considerations and Dissemination
4.2. Public Involvement
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Abbreviations
| AESAN | Agencia Española de Seguridad Alimentaria y Nutrición |
| AMSTAR-2 | A MeaSurement Tool to Assess Systematic Reviews, version 2 |
| CBUB | Comité de Ética designado por la Comisión de Bioética de la Universidad de Barcelona |
| COMET | Core Outcome Measures in Effectiveness Trials Initiative |
| COMMA | Core Outcomes in Menopause |
| COS | Core Outcome Set |
| EFSA | European Food Safety Authority |
| ESPEN | European Society for Clinical Nutrition and Metabolism |
| FAIR | Findable, Accessible, Interoperable, and Reusable |
| GRADE | Grading of Recommendations Assessment, Development and Evaluation |
| ICHOM | International Consortium for Health Outcomes Measurement |
| MeSH | Medical Subject Headings |
| PI(E)CO(TS) | Population or Problem, Intervention or Exposure, Comparison, Outcomes, Timeframe, Setting or Study Design |
| SR | Systematic Review |
| SSI | Semi-structured interview |
| USDA | United States Department of Agriculture |
| WHO | World Health Organization |
References
- Observatorio de Comunicación Científica. La Información Alimentaria a Debate. ¿Qué Pide la Sociedad? Available online: https://www.upf.edu/web/occ/alimentacion-y-comunicacion (accessed on 25 June 2025).
- European Parliament and Council. Regulation (EC) No 1924/2006 of 20 December 2006 on Nutrition and Health Claims Made on Foods. December 2006. Available online: https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=CELEX:02006R1924-20141213 (accessed on 2 December 2025).
- Suarez-Lledo, V.; Alvarez-Galvez, J. Prevalence of Health Misinformation on Social Media: Systematic Review. J. Med. Internet Res. 2021, 23, e17187. [Google Scholar] [CrossRef]
- Rabassa, M.; Alonso-Coello, P.; Casino, G. Nutrimedia: A novel web-based resource for the general public that evaluates the veracity of nutrition claims using the GRADE approach. PLoS ONE 2020, 15, e0232393. [Google Scholar] [CrossRef]
- Fassier, P.; Chhim, A.S.; Andreeva, V.A.; Hercberg, S.; Latino-Martel, P.; Pouchieu, C.; Touvier, M. Seeking health- and nutrition-related information on the Internet in a large population of French adults: Results of the NutriNet-Santé study. Br. J. Nutr. 2016, 115, 2039–2046. [Google Scholar] [CrossRef]
- Svendsen, K.; Torheim, L.E.; Fjelberg, V.; Sorprud, A.; Narverud, I.; Retterstøl, K.; Bogsrud, M.P.; Holven, K.B.; Myhrstad, M.C.W.; Telle-Hansen, V.H. Gender differences in nutrition literacy levels among university students and employees: A descriptive study. J. Nutr. Sci. 2021, 10, e56. [Google Scholar] [CrossRef]
- Davies, E.; Halliday, V. Nutrition information and the menopause: An online survey of perimenopausal and menopausal women. Post Reprod. Health 2024, 31, 65–72. [Google Scholar] [CrossRef]
- Storr, T.; Maher, J.; Swanepoel, E. Online nutrition information for pregnant women: A content analysis. Matern. Child Nutr. 2017, 13, e12315. [Google Scholar] [CrossRef]
- Sedrak, M.S.; Soto-Perez-De-Celis, E.; Nelson, R.A.; Liu, J.; Waring, M.E.; Lane, D.S.; Paskett, E.D.; Chlebowski, R.T. Online health information–seeking among older women with chronic illness: Analysis of the women’s health initiative. Med. Internet Res. 2020, 22, e15906. [Google Scholar] [CrossRef]
- Diyab, R.; Grgurevic, J.; Roy, R. Exploring nutrition misinformation on social media platforms. Proc. Nutr. Soc. 2025, 84, e8. [Google Scholar] [CrossRef]
- Statista. Number of Instagram Users Worldwide from 2020 to 2025 (in Millions). Available online: https://www.statista.com/statistics/183585/instagram-number-of-global-users/ (accessed on 25 June 2025).
- Muralidhara, S.; Paul, M.J. #Healthy Selfies: Exploration of Health Topics on Instagram. JMIR Public Health Surveill. 2018, 4, e10150. [Google Scholar] [CrossRef]
- Segado-Fernández, S.; Jiménez-Gómez, B.; Jiménez-Hidalgo, P.J.; Lozano-Estevan, M.D.C.; Herrera-Peco, I. Disinformation about diet and nutrition on social networks: A review of the literature. Nutr. Hosp. 2025, 42, 366–375. [Google Scholar] [CrossRef]
- Sørensen, K.; Pelikan, J.M.; Röthlin, F.; Ganahl, K.; Slonska, Z.; Doyle, G.; Fullam, J.; Kondilis, B.; Agrafiotis, D.; Uiters, E.; et al. Health literacy in Europe: Comparative results of the European health literacy survey (HLS-EU). Eur. J. Public Health 2015, 25, 1053–1058. [Google Scholar] [CrossRef]
- Tamayo-Fonseca, N.; Pereyra-Zamora, P.; Barona, C.; Mas, R.; Irles, M.Á.; Nolasco, A. Health literacy: Association with socioeconomic determinants and the use of health services in Spain. Front. Public Health 2023, 11, 1226420. [Google Scholar] [CrossRef]
- Williams, G.; Hamm, M.P.; Shulhan, J.; Vandermeer, B.; Hartling, L. Social media interventions for diet and exercise behaviours: A systematic review and meta-analysis of randomised controlled trials. BMJ Open 2014, 4, e003926. [Google Scholar] [CrossRef]
- John, J.N.; Gorman, S.; Scales, D.; Gorman, J. Online misleading information about women’s reproductive health: A narrative review. J. Gen. Intern. Med. 2025, 40, 1123–1131. [Google Scholar] [CrossRef]
- Marcon, A.R.; Bieber, M.; Azad, M.B. Protecting, promoting, and supporting breastfeeding on Instagram. Matern. Child Nutr. 2019, 15, e12658. [Google Scholar] [CrossRef]
- Weiss, R. Menopause and social media: Pros and cons for the general public. Maturitas 2023, 174, 67–68. [Google Scholar] [CrossRef]
- Paul, B.; Headley-Johnson, S.A. The impact of social media on health behaviors, a systematic review. Healthcare 2025, 13, 2763. [Google Scholar] [CrossRef]
- Feskens, E.J.M.; Bailey, R.; Bhutta, Z.; Biesalski, H.K.; Eicher-Miller, H.; Krämer, K.; Pan, W.H.; Griffiths, J.C. Women’s health: Optimal nutrition throughout the lifecycle. Eur. J. Nutr. 2022, 61, 1–23. [Google Scholar] [CrossRef]
- Makarova, N.; Zyriax, B.C. Nutrition and Specific Diseases in Women during the Life Course. Nutrients 2023, 15, 3401. [Google Scholar] [CrossRef]
- Esmaeilinezhad, Z.; Torbahn, G.; Johnston, B.C. MNT Evidence Update: Comparative Effectiveness of Dietary Programs for Reducing Mortality and Cardiovascular Events in Adults with Increased Cardiovascular Risk. Adv. Nutr. 2025, 16, 100399. [Google Scholar] [CrossRef]
- Borges do Nascimento, I.J.; Pizarro, A.B.; Almeida, J.M.; Azzopardi-Muscat, N.; Gonçalves, M.A.; Björklund, M.; Novillo-Ortiz, D. Infodemics and health misinformation: A systematic review of reviews. Bull. World Health Organ. 2022, 100, 544–561. [Google Scholar] [CrossRef]
- Nguyen, V.; Testa, L.; Smith, A.L.; Ellis, L.A.; Dunn, A.G.; Braithwaite, J.; Sarkies, M. Unravelling the truth: Examining the evidence for health-related claims made by naturopathic influencers on social media—A retrospective analysis. Health Promot. Perspect. 2022, 12, 372–380. [Google Scholar] [CrossRef]
- National Institutes of Health. Nutrient Recommendations and Databases. Available online: https://odphp.health.gov/our-work/nutrition-physical-activity/dietary-guidelines/dietary-reference-intakes (accessed on 25 June 2025).
- European Commission. Food-Based Dietary Guidelines in Europe. Available online: https://knowledge4policy.ec.europa.eu/health-promotion-knowledge-gateway/topic/food-based-dietary-guidelines-europe_en (accessed on 25 June 2025).
- Byrne, P.; Daly, A.; Mac Loughlin, D.; Madden, C.; Mc Donnell, T.; O’Connell, C.; Pope, J.; Saif-Ur-Rahman, K.M.; Taneri, P.E.; Tierney, M.; et al. iHealthFacts: A health fact-checking website for the public. BMJ Evid. Based Med. 2024, 29, 415–418. [Google Scholar] [CrossRef]
- Adler, H.; Lewis, M.; Ng, C.H.M.; Brooks, C.; Leonardi, M.; Mikocka-Walus, A.; Bush, D.; Semprini, A.; Wilkinson-Tomey, J.; Condous, G.; et al. Social media, endometriosis, and evidence-based information: An analysis of Instagram Content. Healthcare 2024, 12, 121. [Google Scholar] [CrossRef]
- Denniss, E.; Lindberg, R.; McNaughton, S.A. Development of Principles for Health-Related Information on Social Media: Delphi Study. J. Med. Internet Res. 2022, 24, e37337. [Google Scholar] [CrossRef]
- Prados-Bo, A.; Rabassa, M.; Bosch, M.; Casino, G. Online information in Spanish on probiotics, yoghurt, kefir, kombucha, fibre and prebiotics: An analysis of the quality of information and the certainty of the evidence supporting health claims. BMJ Open 2022, 12, e063316. [Google Scholar] [CrossRef]
- Kiger, M.E.; Varpio, L. Thematic analysis of qualitative data: AMEE Guide No. 131. Med. Teach. 2020, 42, 846–854. [Google Scholar] [CrossRef]
- World Health Organization. Research on the Menopause in the 1990s: Report of a WHO Scientific Group; World Health Organization: Geneva, Switzerland, 1996; Volume 866, pp. 1–107. [Google Scholar]
- Ellis, C.H.; Moore, J.B.; Ho, P.; Evans, C.E.L. Development and validation of a quality assessment tool to assess online nutrition information. Digit. Health 2023, 9, 20552076231187249. [Google Scholar] [CrossRef]
- Cumpston, M.; Flemyng, E. Chapter II: Planning a Cochrane Review. In Cochrane Handbook for Systematic Reviews of Interventions, 2nd ed.; Higgins, J.P.T., Thomas, J., Chandler, J., Cumpston, M., Li, T., Page, M.J., Welch, V.A., Eds.; Cochrane: London, UK, 2023; Available online: https://www.cochrane.org/authors/handbooks-and-manuals/handbook/current/chapter-02 (accessed on 25 June 2025).
- Roqué, M.; Martínez-García, L.; Solà, I.; Alonso-Coello, P.; Bonfill, X.; Zamora, J. Toolkit of methodological resources to conduct systematic reviews. F1000Research 2020, 9, 82. [Google Scholar] [CrossRef]
- Guyatt, G.H.; Oxman, A.D.; Vist, G.E.; Kunz, R.; Falck-Ytter, Y.; Alonso-Coello, P.; Schünemann, H.J. GRADE: An emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008, 336, 924–926. [Google Scholar] [CrossRef]
- Shea, B.J.; Reeves, B.C.; Wells, G.; Thuku, M.; Hamel, C.; Moran, J.; Moher, D.; Tugwell, P.; Welch, V.; Kristjansson, E.; et al. AMSTAR 2: A critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ 2017, 358, j4008. [Google Scholar] [CrossRef] [PubMed]
- Harlow, S.D.; Derby, C.A. Women’s Midlife Health: Why the midlife matters. Womens Midlife Health 2015, 1, 5. [Google Scholar] [CrossRef] [PubMed]
- Barber, K.; Charles, A. Barriers to accessing effective treatment and support for menopausal symptoms: A qualitative study capturing the behaviours, beliefs and experiences of key stakeholders. Patient Prefer. Adherence 2023, 17, 2971–2980. [Google Scholar] [CrossRef]
- Lee, H.; Junghee, K.; Lee, H. Development and validation of a menopause-specific health literacy scale for middle-aged women. Patient Educ. Couns. 2025, 136, 108762. [Google Scholar] [CrossRef]
- Hickey, M.; LaCroix, A.Z.; Doust, J.; Mishra, G.D.; Sivakami, M.; Garlick, D.; Hunter, M.S. An empowerment model for managing menopause. Lancet 2024, 403, 947–957. [Google Scholar] [CrossRef] [PubMed]
- Snyder, L.B.; Newton, K.M.; Ng, H.X.; Reed, S.D.; Guthrie, K.A.; Zambrano, V.; LaCroix, A.Z. Positive impact of a menopause website—MyMenoplan.org—On treatment intentions, knowledge, and decision making: A randomized controlled trial. Maturitas 2025, 199, 108630. [Google Scholar] [CrossRef]
- Lycke, A.; Brorsson, A. Swedish women’s experiences of menopausal transition: A focus group study. Sex. Reprod. Healthc. 2023, 35, 100807. [Google Scholar] [CrossRef]
- Malterud, K. Systematic text condensation: A strategy for qualitative analysis. Scand. J. Public Health 2012, 40, 795–805. [Google Scholar] [CrossRef]
- Davies, T.W.; Watson, N.; Pilkington, J.J.; McClelland, T.J.; Azzopardi, G.; Pearse, R.M.; Prowle, J.; Puthucheary, Z. Creatine supplementation for optimization of physical function in the patient at risk of functional disability: A systematic review and meta-analysis. JPEN J. Parenter. Enter. Nutr. 2024, 48, 389–405. [Google Scholar] [CrossRef]
- Maughan, R.J.; Burke, L.M.; Dvorak, J.; Larson-Meyer, D.E.; Peeling, P.; Phillips, S.M.; Rawson, E.S.; Walsh, N.P.; Garthe, I.; Geyer, H.; et al. IOC consensus statement: Dietary supplements and the high-performance athlete. Br. J. Sports Med. 2018, 52, 439–455. [Google Scholar] [CrossRef]
- EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies). Scientific Opinion on Dietary Reference Values for protein. EFSA J. 2012, 10, 2557. [Google Scholar] [CrossRef]
- Morton, R.W.; Murphy, K.T.; McKellar, S.R.; Schoenfeld, B.J.; Henselmans, M.; Helms, E.; Aragon, A.A.; Devries, M.C.; Banfield, L.; Krieger, J.W.; et al. A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults. Br. J. Sports Med. 2018, 52, 376–384. [Google Scholar] [CrossRef] [PubMed]
- Comité Científico AESAN; Gutiérrez, Á.; Gil, Á.; Aguilera, C.M.; Bretón, I.; Nieto, G.; Pichardo, S.; Sánchez, M.C. Informe del Comité Científico de la Agencia Española de Seguridad Alimentaria y Nutrición (AESAN) en relación con el riesgo asociado al consumo de complementos alimenticios que contienen creatina como ingrediente. Rev. Comité Científico AESAN 2024, 39, 47–62. [Google Scholar]

| Term | Definition 1 |
|---|---|
| Nutrient recommendations (or dietary reference intakes) [26] | Recommendations that define the daily intake levels of essential nutrients (expressed in units such as mg or g per day) that are considered adequate to meet the physiological needs of almost all healthy individuals in a population. |
| Dietary recommendations (or dietary guidelines, also known as food-based dietary guidelines [27] | Science-based guidelines that provide advice for populations on healthy eating patterns. Rather than focusing on individual nutrients, dietary recommendations guide food decisions to promote overall health and prevent chronic diseases. They are designed to support informed decisions about diet and lifestyle at the population level. |
| Claim [28] | Our use of the term ‘nutrition claims’ is not related to food product labeling or marketing but rather to general health-related statements or assertions that can impact women’s health. |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.
Share and Cite
Bosch Pujadas, M.; Prados-Bo, A.; Wagner, A.; Johnston, B.C.; Farran-Codina, A.; Rabassa, M. NutriWomen, Novel Evidence-Based Web Platform to Support Women’s Health, Nutrition Decisions and Address Nutrition Misinformation on Social Media: Protocol for a Digital Tool Development. Nutrients 2026, 18, 20. https://doi.org/10.3390/nu18010020
Bosch Pujadas M, Prados-Bo A, Wagner A, Johnston BC, Farran-Codina A, Rabassa M. NutriWomen, Novel Evidence-Based Web Platform to Support Women’s Health, Nutrition Decisions and Address Nutrition Misinformation on Social Media: Protocol for a Digital Tool Development. Nutrients. 2026; 18(1):20. https://doi.org/10.3390/nu18010020
Chicago/Turabian StyleBosch Pujadas, Mireia, Andreu Prados-Bo, Alessandra Wagner, Bradley C. Johnston, Andreu Farran-Codina, and Montserrat Rabassa. 2026. "NutriWomen, Novel Evidence-Based Web Platform to Support Women’s Health, Nutrition Decisions and Address Nutrition Misinformation on Social Media: Protocol for a Digital Tool Development" Nutrients 18, no. 1: 20. https://doi.org/10.3390/nu18010020
APA StyleBosch Pujadas, M., Prados-Bo, A., Wagner, A., Johnston, B. C., Farran-Codina, A., & Rabassa, M. (2026). NutriWomen, Novel Evidence-Based Web Platform to Support Women’s Health, Nutrition Decisions and Address Nutrition Misinformation on Social Media: Protocol for a Digital Tool Development. Nutrients, 18(1), 20. https://doi.org/10.3390/nu18010020

