Next Article in Journal
Association of Dietary n3 and n6 Fatty Acids Intake with Hypertension: NHANES 2007–2014
Next Article in Special Issue
Modulation of Bone and Marrow Niche by Cholesterol
Previous Article in Journal
Effect of 1 Year Krill Oil Supplementation on Cognitive Achievement of Dutch Adolescents: A Double-Blind Randomized Controlled Trial
Previous Article in Special Issue
Frequency and Quantity of Egg Intake Is Not Associated with Dyslipidemia: The Hellenic National Nutrition and Health Survey (HNNHS)
Article Menu
Issue 6 (June) cover image

Export Article

Open AccessReview

Relationship Between HDL Functional Characteristics and Cardiovascular Health and Potential Impact of Dietary Patterns: A Narrative Review

Department of Nutrition and Graduate Group in Nutritional Biology, University of California, Davis, CA 95616, USA
*
Author to whom correspondence should be addressed.
Nutrients 2019, 11(6), 1231; https://doi.org/10.3390/nu11061231
Received: 10 April 2019 / Revised: 25 May 2019 / Accepted: 27 May 2019 / Published: 30 May 2019
(This article belongs to the Special Issue Cholesterol and Nutrition)
  |  
PDF [258 KB, uploaded 30 May 2019]

Abstract

Cardiovascular disease is a leading cause of death around the world. Overall diet quality and dietary behaviors are core contributors to metabolic health. While therapeutic targets have traditionally focused on levels of lipoprotein cholesterol when evaluating cardiovascular risk, current perspectives on high-density lipoprotein (HDL) have shifted to evaluating the functionality of this lipoprotein particle. Effects of diet on cardiovascular health are mediated through multiple pathways, but the impact on HDL composition and function deserves greater attention. Potential areas of investigation involve changes in particle characteristics, distribution, microRNA cargo, and other functional changes such as improvements to cholesterol efflux capacity. Various dietary patterns like the Mediterranean diet and Dietary Approaches to Stop Hypertension (DASH) diet have beneficial effects on cardiovascular health and may prevent cardiovascular events. These healthful dietary patterns tend to be rich in plant-based foods, with cardiovascular benefits likely resulting from synergistic effects of the individual dietary components. The purpose of this review is to summarize current perspectives on selected functions of HDL particles and how various dietary patterns affect cardiovascular health biomarkers, with a focus on HDL functionality. View Full-Text
Keywords: HDL; HDL functionality; cardiovascular; prevention; nutrition; dietary pattern; DASH; Mediterranean; prudent diet HDL; HDL functionality; cardiovascular; prevention; nutrition; dietary pattern; DASH; Mediterranean; prudent diet
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

Supplementary material

SciFeed

Share & Cite This Article

MDPI and ACS Style

Bardagjy, A.S.; Steinberg, F.M. Relationship Between HDL Functional Characteristics and Cardiovascular Health and Potential Impact of Dietary Patterns: A Narrative Review. Nutrients 2019, 11, 1231.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top