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Influence of Bioactive Nutrients on the Atherosclerotic Process: A Review

1
Department of Internal Medicine, Hospital Clinic, Institut d’Investigació Biomèdica August Pi i Sunyer (IDIBAPS), University of Barcelona, Villarroel, 170, 08036 Barcelona, Spain
2
CIBER 06/03: Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III, 28029 Madrid, Spain
*
Author to whom correspondence should be addressed.
Nutrients 2018, 10(11), 1630; https://doi.org/10.3390/nu10111630
Received: 18 September 2018 / Revised: 19 October 2018 / Accepted: 26 October 2018 / Published: 2 November 2018
(This article belongs to the Special Issue Nutrients and Atherosclerosis)
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PDF [698 KB, uploaded 2 November 2018]
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Abstract

The protective effects of a dietary intervention as a useful tool in the prevention of atherosclerosis disease has gained greater attention in recent years. Several epidemiological studies have demonstrated the importance of diet in reducing expensive treatments or possible undesirable side effects. The main aim of this review is to examine the effects of specific nutrients on the development and progression of atherosclerosis in patients with cardiovascular disease. Various mechanisms have been proposed to explain the cardioprotective effect of different nutrients. In this sense, results have shown stabilization of vulnerable atherosclerotic plaques or downregulation of biomarkers related to inflammation through nutrients such as Omega-3 polyunsaturated fatty acids, hydroxytyrosol of extra virgin olive oil, lycopen, phytosterols of plants, or flavonols of fruits and vegetables, among others. The accumulated evidence on the anti-inflammatory effects related to these nutrients is summarized in the present review. View Full-Text
Keywords: CVD; atherosclerosis; hydroxytyrosol; inflammation; nutrients; polyphenols; PUFA; bioactive compounds; phytosterols CVD; atherosclerosis; hydroxytyrosol; inflammation; nutrients; polyphenols; PUFA; bioactive compounds; phytosterols
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Casas, R.; Estruch, R.; Sacanella, E. Influence of Bioactive Nutrients on the Atherosclerotic Process: A Review. Nutrients 2018, 10, 1630.

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