Next Article in Journal
Right-Sided Endocarditis from Staphylococcus Lugdunensis in a Patient with Tetralogy of Fallot
Previous Article in Journal
Changes in the Incidence and Epidemiology of Neonatal Group B Streptococcal Disease over the Last Two Decades in Crete, Greece
 
 
Infectious Disease Reports is published by MDPI from Volume 12 Issue 3 (2020). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Mycetoma in Timor-Leste and First Report of Nocardiosis

1
Infectious Disease Department, Sunshine Coast University Hospital, Queensland, Australia
2
Department of Infection, Sheffield Teaching Hospitals, UK
3
Bairo-Pite Clinic, Bairo-Pite, Timor-Leste
4
Infectious Disease Department, Royal Darwin Hospital, Northern Territories, Australia
5
Maluk Timor, Dili, Timor-Leste
6
Menzies School of Health Research (Global & Tropical Health Division), Australia
7
Lady Cilento Children’s Hospital, Brisbane, Australia
*
Author to whom correspondence should be addressed.
Infect. Dis. Rep. 2018, 10(3), 7804; https://doi.org/10.4081/idr.2018.7804
Submission received: 29 July 2018 / Revised: 10 October 2018 / Accepted: 19 October 2018 / Published: 12 December 2018

Abstract

Mycetoma is a neglected tropical disease with an unknown global burden. Although considered endemic to South-east Asia, it has not previously been reported from Timor-Lest. We describe two cases in Timor-Leste, highlighting the challenges surrounding microbiological diagnosis and management shared by many low to middle-income countries. As characteristically described, both patients lived rurally and presented late with marked soft tissue involvement and multiple draining sinuses following a prolonged period of high morbidity. Nocardia brasiliensis, a beadedbranched, modified acid-fast, gram-positive bacilli, was isolated and confirmed by molecular testing in the first case. The causative organism in the second case could not be confirmed due to limited microbiological capabilities. Due to limited local laboratory capabilities, Nocardia spp. infection cannot be routinely confirmed in Timor- Leste. However, the microbiology laboratory is essential for the successful diagnosis and management of Mycetoma. In both cases, medical therapy alone resulted in cure and favorable outcomes, although supply of antibiotic remains an ongoing resource issue.
Keywords: nocardia; mycetoma; timor-leste nocardia; mycetoma; timor-leste

Share and Cite

MDPI and ACS Style

Townell, N.; Locke, T.; Gibbons, M.; Murphy, D.; Francis, J.; Nourse, C. Mycetoma in Timor-Leste and First Report of Nocardiosis. Infect. Dis. Rep. 2018, 10, 7804. https://doi.org/10.4081/idr.2018.7804

AMA Style

Townell N, Locke T, Gibbons M, Murphy D, Francis J, Nourse C. Mycetoma in Timor-Leste and First Report of Nocardiosis. Infectious Disease Reports. 2018; 10(3):7804. https://doi.org/10.4081/idr.2018.7804

Chicago/Turabian Style

Townell, Nicola, Thomas Locke, Margaret Gibbons, Dan Murphy, Joshua Francis, and Clare Nourse. 2018. "Mycetoma in Timor-Leste and First Report of Nocardiosis" Infectious Disease Reports 10, no. 3: 7804. https://doi.org/10.4081/idr.2018.7804

Article Metrics

Back to TopTop