Fabrication of Carbonate Apatite Block through a Dissolution–Precipitation Reaction Using Calcium Hydrogen Phosphate Dihydrate Block as a Precursor

Tsuru, Kanji; Yoshimoto, Ayami; Kanazawa, Masayuki; Sugiura, Yuki; Nakashima, Yasuharu; Ishikawa, Kunio

doi:10.3390/ma10040374

Open AccessArticle

Fabrication of Carbonate Apatite Block through a Dissolution–Precipitation Reaction Using Calcium Hydrogen Phosphate Dihydrate Block as a Precursor

by

Kanji Tsuru

^1,*,

Ayami Yoshimoto

¹,

Masayuki Kanazawa

²,

Yuki Sugiura

¹,

Yasuharu Nakashima

² and

Kunio Ishikawa

¹

Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

²

Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan

^*

Author to whom correspondence should be addressed.

Materials 2017, 10(4), 374; https://doi.org/10.3390/ma10040374

Submission received: 27 January 2017 / Revised: 23 March 2017 / Accepted: 29 March 2017 / Published: 31 March 2017

(This article belongs to the Special Issue Bioceramics 2016)

Download

Browse Figures

Versions Notes

Abstract

Carbonate apatite (CO₃Ap) block, which is a bone replacement used to repair defects, was fabricated through a dissolution–precipitation reaction using a calcium hydrogen phosphate dihydrate (DCPD) block as a precursor. When the DCPD block was immersed in NaHCO₃ or Na₂CO₃ solution at 80 °C, DCPD converted to CO₃Ap within 3 days. β-Tricalcium phosphate was formed as an intermediate phase, and it was completely converted to CO₃Ap within 2 weeks when the DCPD block was immersed in Na₂CO₃ solution. Although the crystal structures of the DCPD and CO₃Ap blocks were different, the macroscopic structure was maintained during the compositional transformation through the dissolution–precipitation reaction. CO₃Ap block fabricated in NaHCO₃ or Na₂CO₃ solution contained 12.9 and 15.8 wt % carbonate, respectively. The diametral tensile strength of the CO₃Ap block was 2 MPa, and the porosity was approximately 57% regardless of the carbonate solution. DCPD is a useful precursor for the fabrication of CO₃Ap block.

Keywords: bone replacement; carbonate apatite; calcium hydrogen phosphate dihydrate; dissolution–precipitation reaction

Share and Cite

MDPI and ACS Style

Tsuru, K.; Yoshimoto, A.; Kanazawa, M.; Sugiura, Y.; Nakashima, Y.; Ishikawa, K. Fabrication of Carbonate Apatite Block through a Dissolution–Precipitation Reaction Using Calcium Hydrogen Phosphate Dihydrate Block as a Precursor. Materials 2017, 10, 374. https://doi.org/10.3390/ma10040374

AMA Style

Tsuru K, Yoshimoto A, Kanazawa M, Sugiura Y, Nakashima Y, Ishikawa K. Fabrication of Carbonate Apatite Block through a Dissolution–Precipitation Reaction Using Calcium Hydrogen Phosphate Dihydrate Block as a Precursor. Materials. 2017; 10(4):374. https://doi.org/10.3390/ma10040374

Chicago/Turabian Style

Tsuru, Kanji, Ayami Yoshimoto, Masayuki Kanazawa, Yuki Sugiura, Yasuharu Nakashima, and Kunio Ishikawa. 2017. "Fabrication of Carbonate Apatite Block through a Dissolution–Precipitation Reaction Using Calcium Hydrogen Phosphate Dihydrate Block as a Precursor" Materials 10, no. 4: 374. https://doi.org/10.3390/ma10040374

APA Style

Tsuru, K., Yoshimoto, A., Kanazawa, M., Sugiura, Y., Nakashima, Y., & Ishikawa, K. (2017). Fabrication of Carbonate Apatite Block through a Dissolution–Precipitation Reaction Using Calcium Hydrogen Phosphate Dihydrate Block as a Precursor. Materials, 10(4), 374. https://doi.org/10.3390/ma10040374

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Menu

Fabrication of Carbonate Apatite Block through a Dissolution–Precipitation Reaction Using Calcium Hydrogen Phosphate Dihydrate Block as a Precursor

Abstract

Share and Cite

Article Metrics

Article Access Statistics

Further Information

Guidelines

MDPI Initiatives

Follow MDPI