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Cardiovascular Medicine
Volume 18
Issue 5
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Cardiovascular Medicine is published by MDPI from Volume 28 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Editores Medicorum Helveticorum (EMH).

Cardiovasc. Med., Volume 18, Issue 5 (05 2015) – 5 articles

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2 pages, 69 KB  
Communication
What Are the Current Blood Pressure Targets?
by Andreas W. Schoenenberger and Paul Erne
Cardiovasc. Med. 2015, 18(5), 177; https://doi.org/10.4414/cvm.2015.00337 - 27 May 2015
Viewed by 10
Abstract
Recommendations for blood pressure (BP) targets of hypertensive subjects undergoing antihypertensive treatment have become confusing in recent years according to official guidelines [...] Full article
5 pages, 186 KB  
Editorial
LCZ696—a Promising New Compound in Heart Failure Treatment
by Roger Hullin
Cardiovasc. Med. 2015, 18(5), 173; https://doi.org/10.4414/cvm.2015.00330 (registering DOI) - 27 May 2015
Viewed by 11
Abstract
LCZ696 is an angiotensin receptor neprilysin inhibitor (ARNI) composed of the angiotensin receptor inhibitor valsartan and the neprilysin inhibitor AHU377. This compound molecule has proven efficiency in mild to moderate arterial hypertension and in heart failure patients with preserved ejection fraction, and has [...] Read more.
LCZ696 is an angiotensin receptor neprilysin inhibitor (ARNI) composed of the angiotensin receptor inhibitor valsartan and the neprilysin inhibitor AHU377. This compound molecule has proven efficiency in mild to moderate arterial hypertension and in heart failure patients with preserved ejection fraction, and has been shown to be superior to enalapril treatment in patients presenting with moderate to severe heart failure due to reduced left ventricular ejection fraction. The present overview will summarise pathophysiological and pharmacological aspects of this compound molecule, discuss results from clinical studies, and provide an outlook on the future role of this molecule in heart failure treatment. Full article
5 pages, 154 KB  
Article
Switching from Femoral to Radial Access for Coronary Angiography in ACS
by Ivano Reho, Martin Sprenger, David Tueller, Britta Bottignole, David J. Kurz, Alain Bernheim, Franz Robert Eberli and Rainer Zbinden
Cardiovasc. Med. 2015, 18(5), 169; https://doi.org/10.4414/cvm.2015.00332 - 27 May 2015
Viewed by 9
Abstract
Background: Transradial access (TRA) for coronary angiography (CA) is thought to be superior to the transfemoral approach (TFA) in patients presenting with an acute coronary syndrome (ACS) regarding access site complications and bleeding events. As an institution that primarily uses TFA for [...] Read more.
Background: Transradial access (TRA) for coronary angiography (CA) is thought to be superior to the transfemoral approach (TFA) in patients presenting with an acute coronary syndrome (ACS) regarding access site complications and bleeding events. As an institution that primarily uses TFA for CA, we switched to TRA during the year 2012. The aim of this study was to look for differences in bleeding events, procedure times, contrast use in ACS patients and door-to-balloon (dtb) times in STEMI patients comparing the TRA and TFA, respectively. Methods/results: A total of 789 ACS patients underwent CA in 2012. Of these, 502 patients had the TFA and 287 patients the TRA for CA. The overall bleeding rate was 14.1% for TFA and 5.3% for TRA (p < 0.01) using the BARC (bleeding academic research consortium) criteria. Access siterelated bleeding events were 10.5% in the TFA group and 3.9% in the TRA group (p = 0.01). There were no differences regarding procedure times or contrast use between the two groups. In a multivariate analysis, gender, age, Gp IIb/IIIa use and access site were independent predictors of bleeding events. Of the 789 patients, 428 were STEMI patients. Dtb time was 106 ± 100 min (including transfer patients). There was no difference regarding dtb time between the TRA and the TFA group. Conclusion: For experienced “femoral operators”, a switch to the radial access site is feasible and safe. There is no increase in dtb time, fluoroscopy time or contrast use, but a significant decrease in bleeding events with the radial approach in patients presenting with ACS. Full article
7 pages, 507 KB  
Review
EKG bei akuten Koronarsyndromen
by Christophe Wyss
Cardiovasc. Med. 2015, 18(5), 163; https://doi.org/10.4414/cvm.2015.00321 (registering DOI) - 27 May 2015
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Abstract
Electrocardiogram during acute coronary syndromes. The electrocardiogram (ECG) has a key role in the diagnosis and management of acute coronary syndrome (ACS). Besides recognising typical ECG patterns, we should be aware of atypical presentations. There is a broad range of different explanations for [...] Read more.
Electrocardiogram during acute coronary syndromes. The electrocardiogram (ECG) has a key role in the diagnosis and management of acute coronary syndrome (ACS). Besides recognising typical ECG patterns, we should be aware of atypical presentations. There is a broad range of different explanations for repolarisation changes without the presence of ACS. Prehospital ECGs have a direct impact on the processes of care and mortality in ACS. Full article
10 pages, 615 KB  
Review
Real-Time Contact Force Measurement for Catheter Ablation of Cardiac Arrhythmias
by Mehdi Namdar and Dipen C. Shah
Cardiovasc. Med. 2015, 18(5), 155; https://doi.org/10.4414/cvm.2015.00313 (registering DOI) - 27 May 2015
Cited by 2 | Viewed by 11
Abstract
Radiofrequency (RF) energy nowadays enjoys an indisputable value as the dominant energy source for the treatment of various arrhythmias amenable to catheter ablation, which has gradually replaced surgical techniques for the treatment of supraventricular and ventricular arrhythmias with electric, thermal, light, mechanical and [...] Read more.
Radiofrequency (RF) energy nowadays enjoys an indisputable value as the dominant energy source for the treatment of various arrhythmias amenable to catheter ablation, which has gradually replaced surgical techniques for the treatment of supraventricular and ventricular arrhythmias with electric, thermal, light, mechanical and chemical means. It has become obvious in recent years that the success and sustainable effect of the ablation may depend on a critical understanding of the biophysics of lesion creation and its control. Full article
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