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Review

Current Narrative Review—Application of Blood Flow Restriction Exercise in Clinical Knee Problems

1
Department of Orthopaedic Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul 05030, Republic of Korea
2
Department of Orthopedic Surgery, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu 42601, Republic of Korea
*
Author to whom correspondence should be addressed.
Medicina 2025, 61(8), 1377; https://doi.org/10.3390/medicina61081377
Submission received: 22 June 2025 / Revised: 2 July 2025 / Accepted: 28 July 2025 / Published: 30 July 2025
(This article belongs to the Special Issue Cutting-Edge Concepts in Knee Surgery)

Abstract

Quadricep weakness is frequently observed in patients following anterior cruciate ligament (ACL) injury or in those with knee osteoarthritis, often contributing to functional impairments and persistent symptoms. While high-intensity resistance training has been shown to effectively improve muscle strength, its application may be limited in certain populations due to pain or the risk of surgical complications. In recent years, blood flow restriction (BFR) training has emerged as a promising alternative. Growing evidence indicates that low-load BFR exercise can significantly improve muscle strength, induce hypertrophy, and enhance knee function, with outcomes comparable to those of high-intensity resistance training. When implemented using appropriate protocols, BFR training appears to be a safe and efficacious rehabilitation strategy for individuals with knee pathology.
Keywords: blood flow restriction; exercise; quadriceps muscle; anterior cruciate ligament reconstruction; knee osteoarthritis blood flow restriction; exercise; quadriceps muscle; anterior cruciate ligament reconstruction; knee osteoarthritis

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MDPI and ACS Style

Kwon, S.; Bae, K.-C.; Yon, C.-J.; Kim, D.-H. Current Narrative Review—Application of Blood Flow Restriction Exercise in Clinical Knee Problems. Medicina 2025, 61, 1377. https://doi.org/10.3390/medicina61081377

AMA Style

Kwon S, Bae K-C, Yon C-J, Kim D-H. Current Narrative Review—Application of Blood Flow Restriction Exercise in Clinical Knee Problems. Medicina. 2025; 61(8):1377. https://doi.org/10.3390/medicina61081377

Chicago/Turabian Style

Kwon, Saehim, Ki-Cheor Bae, Chang-Jin Yon, and Du-Han Kim. 2025. "Current Narrative Review—Application of Blood Flow Restriction Exercise in Clinical Knee Problems" Medicina 61, no. 8: 1377. https://doi.org/10.3390/medicina61081377

APA Style

Kwon, S., Bae, K.-C., Yon, C.-J., & Kim, D.-H. (2025). Current Narrative Review—Application of Blood Flow Restriction Exercise in Clinical Knee Problems. Medicina, 61(8), 1377. https://doi.org/10.3390/medicina61081377

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