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Review

The Role of Plant-Based Diets and Personalized Nutrition in Endometriosis Management: A Review

by
Marijana Matek Sarić
1,
Tamara Sorić
2,*,
Ana Sarić
3,
Emili Marušić
4,
Miran Čoklo
5,
Mladen Mavar
2,
Marija Ljubičić
1 and
Nataša Lisica Šikić
1
1
Department of Health Studies, University of Zadar, Splitska 1, 23000 Zadar, Croatia
2
Psychiatric Hospital Ugljan, Otočkih dragovoljaca 42, 23275 Ugljan, Croatia
3
School of Medicine, Catholic University of Croatia, Ilica 242, 10000 Zagreb, Croatia
4
Department of Pediatrics, General Hospital Zadar, Bože Peričića 5, 23000 Zadar, Croatia
5
Institute for Anthropological Research, Ljudevita Gaja 32, 10000 Zagreb, Croatia
*
Author to whom correspondence should be addressed.
Medicina 2025, 61(7), 1264; https://doi.org/10.3390/medicina61071264
Submission received: 11 June 2025 / Revised: 9 July 2025 / Accepted: 11 July 2025 / Published: 13 July 2025
(This article belongs to the Section Obstetrics and Gynecology)
Review Reports Versions Notes

Abstract

Endometriosis is a chronic, estrogen-dependent inflammatory condition that affects multiple organ systems and significantly impairs the quality of life in women of reproductive age. While conventional hormonal therapies may alleviate symptoms of endometriosis, they are also frequently associated with intolerable side effects. As a result, there is growing interest in complementary, non-invasive strategies to support long-term disease management. This review explores the potential of plant-based diets and personalized nutrition as adjunctive approaches in endometriosis care. Plant-based dietary patterns, which are rich in antioxidants, phytochemicals, dietary fiber, and essential micronutrients, have been shown to reduce systemic inflammation, modulate estrogen activity, and alleviate pelvic pain. Additionally, the use of medicinal plants, such as curcumin and ginger, has demonstrated anti-inflammatory and anti-proliferative effects in preclinical studies. Moreover, identifying and addressing individual food sensitivities, particularly to gluten, dairy, or fermentable oligosaccharides, disaccharides, monosaccharides, and polyols, may improve gastrointestinal and inflammatory symptoms in susceptible individuals. Future research should focus on high-quality clinical trials and integrative care models to evaluate the long-term efficacy, safety, and sustainability of these individualized nutritional interventions in the holistic management of endometriosis.
Keywords: endometriosis; plant-based diet; personalized nutrition; sustainable healthcare; holistic approach endometriosis; plant-based diet; personalized nutrition; sustainable healthcare; holistic approach

Share and Cite

MDPI and ACS Style

Matek Sarić, M.; Sorić, T.; Sarić, A.; Marušić, E.; Čoklo, M.; Mavar, M.; Ljubičić, M.; Lisica Šikić, N. The Role of Plant-Based Diets and Personalized Nutrition in Endometriosis Management: A Review. Medicina 2025, 61, 1264. https://doi.org/10.3390/medicina61071264

AMA Style

Matek Sarić M, Sorić T, Sarić A, Marušić E, Čoklo M, Mavar M, Ljubičić M, Lisica Šikić N. The Role of Plant-Based Diets and Personalized Nutrition in Endometriosis Management: A Review. Medicina. 2025; 61(7):1264. https://doi.org/10.3390/medicina61071264

Chicago/Turabian Style

Matek Sarić, Marijana, Tamara Sorić, Ana Sarić, Emili Marušić, Miran Čoklo, Mladen Mavar, Marija Ljubičić, and Nataša Lisica Šikić. 2025. "The Role of Plant-Based Diets and Personalized Nutrition in Endometriosis Management: A Review" Medicina 61, no. 7: 1264. https://doi.org/10.3390/medicina61071264

APA Style

Matek Sarić, M., Sorić, T., Sarić, A., Marušić, E., Čoklo, M., Mavar, M., Ljubičić, M., & Lisica Šikić, N. (2025). The Role of Plant-Based Diets and Personalized Nutrition in Endometriosis Management: A Review. Medicina, 61(7), 1264. https://doi.org/10.3390/medicina61071264

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